1,2,3‐Triazole Derivatives as an Emerging Scaffold for Antifungal Drug Development against Candida albicans: A Comprehensive Review
Candida infections are most prominent among fungal infections majorly target
immunocompromised and hospitalized patients and cause significant morbidity and …
immunocompromised and hospitalized patients and cause significant morbidity and …
Click chemistry beyond metal‐catalyzed cycloaddition as a remarkable tool for green chemical synthesis of antifungal medications
A Tahghighi, P Azerang - Chemical Biology & Drug Design, 2024 - Wiley Online Library
Click chemistry is widely used for the efficient synthesis of 1, 4‐disubstituted‐1, 2, 3‐triazole,
a well‐known scaffold with widespread biological activity in the pharmaceutical sciences. In …
a well‐known scaffold with widespread biological activity in the pharmaceutical sciences. In …
Synthesis, biological evaluation and mechanistic studies of 4-(1, 3-thiazol-2-yl) morpholine-benzimidazole hybrids as a new structural class of antimicrobials
In spite of several attempts to develop newer pharmacophores as potential antimicrobial
agents, the benzimidazole scaffold is still considered as one of the most sought after …
agents, the benzimidazole scaffold is still considered as one of the most sought after …
Synthesis, Biological Evaluation, Molecular Docking, and Acid Dissociation Constant of New Bis‐1, 2, 3‐triazole Compounds
In this study, new bis‐1, 2, 3‐triazole derivatives, N, N′‐(1, 3‐phenylene) bis (2‐(4‐R‐1H‐
1, 2, 3‐triazol‐1‐yl) acetamide), were synthesized by copper‐catalyzed azide‐alkyne …
1, 2, 3‐triazol‐1‐yl) acetamide), were synthesized by copper‐catalyzed azide‐alkyne …
Synthesis of new triazole fused imidazo [2, 1-b] thiazole hybrids with emphasis on Staphylococcus aureus virulence factors
MA Shareef, K Sirisha, IB Sayeed, I Khan… - Bioorganic & Medicinal …, 2019 - Elsevier
A series of new triazole fused imidazo [2, 1-b] thiazole hybrids (9a–u) were designed,
synthesized and evaluated as antimicrobial agents. Compounds 9c, 9d, 9e, 9j and 9l …
synthesized and evaluated as antimicrobial agents. Compounds 9c, 9d, 9e, 9j and 9l …
Efficient One-Pot Synthesis of Indolhydroxy Derivatives Catalyzed by SnCl2, DFT Calculations and Docking Study
Y Hakmaoui, A Eşme, RE Ajlaoui, ME Belghiti… - Chemistry Africa, 2022 - Springer
In this work we used an efficient and simple synthesis for the preparation of new
indolhydroxy derivatives that has been performed by the reduction reaction of 2 …
indolhydroxy derivatives that has been performed by the reduction reaction of 2 …
New Indolyl‐Arylaminopropenone Conjugates: Synthesis, Cytotoxicity and Apoptotic Inducing Studies
In view of the antiproliferative potential of indoles and aryl amino propenones, a series of
indolyl tethered aryl aminopropenones have been synthesized and investigated for their anti …
indolyl tethered aryl aminopropenones have been synthesized and investigated for their anti …