Angiotropism, pericytic mimicry and extravascular migratory metastasis: an embryogenesis-derived program of tumor spread

C Lugassy, HK Kleinman, PB Vermeulen, RL Barnhill - Angiogenesis, 2020 - Springer
Intravascular dissemination of tumor cells is the accepted mechanism of cancer metastasis.
However, the phenomenon of angiotropism, pericyte mimicry (PM), and extravascular …

Vessel co-option and angiotropic extravascular migratory metastasis: a continuum of tumour growth and spread?

C Lugassy, PB Vermeulen, D Ribatti, F Pezzella… - British Journal of …, 2022 - nature.com
Two fields of cancer research have emerged dealing with the biology of tumour cells
localised to the abluminal vascular surface: vessel co-option (VCo), a non-angiogenic mode …

Imaging of angiotropism/vascular co-option in a murine model of brain melanoma: implications for melanoma progression along extravascular pathways

LA Bentolila, R Prakash, D Mihic-Probst, M Wadehra… - Scientific reports, 2016 - nature.com
Angiotropism/pericytic mimicry and vascular co-option involve tumor cell interactions with
the abluminal vascular surface. These two phenomena may be closely related. However …

Melanoma tumour vascularization and tissue-resident endothelial progenitor cells

G Hashemi, J Dight, K Khosrotehrani, L Sormani - Cancers, 2022 - mdpi.com
Simple Summary Melanoma is the most aggressive and potentially lethal form of skin
cancer. Research over recent decades has highlighted the role of tumour vasculature in …

Clinical treatment options for early-stage and advanced conjunctival melanoma

Y Zeng, C Hu, L Shu, Y Pan, L Zhao, X Pu, F Wu - Survey of ophthalmology, 2021 - Elsevier
Conjunctival melanoma (CM) is an ocular malignant tumor arising from the bulbar and
palpebral conjunctiva and from the caruncle. The treatment of early-stage CM is wide local …

[HTML][HTML] The biological and prognostic significance of angiotropism in uveal melanoma

RL Barnhill, M Ye, A Batistella, MH Stern… - Laboratory …, 2017 - Elsevier
Angiotropism is a marker of extravascular migration of melanoma cells along vascular and
other structures and a prognostic factor in cutaneous melanoma. Because of this biological …

TFPI2 promotes perivascular migration in an angiotropism model of melanoma

J Mo, X Zhao, W Wang, N Zhao, X Dong… - Frontiers in …, 2021 - frontiersin.org
Purpose Angiotropism is the process by which cancer cells attach to and migrate along
blood vessels to acquire vasculature, disseminate, and metastasize. However, the molecular …

[HTML][HTML] Lymphatic invasion and angiotropism in primary cutaneous melanoma

AP Moy, LM Duncan, S Kraft - Laboratory Investigation, 2017 - Elsevier
Access of melanoma cells to the cutaneous vasculature either via lymphatic invasion or
angiotropism is a proposed mechanism for metastasis. Lymphatic invasion is believed to be …

Angiotropism in primary cutaneous melanoma is associated with disease progression and distant metastases: a retrospective study of 179 cases

AP Moy, LM Duncan, A Muzikansky… - Journal of Cutaneous …, 2019 - Wiley Online Library
Background Angiotropism is the histopathological correlate of pericytic mimicry and
extravascular migratory metastasis (EVMM), a mechanism of melanoma spread by migration …

Pericyte mimicry: An embryogenesis-derived program of extravascular tumor cell migration

C Lugassy, H Kleinman, R Barnhill - Tumor Vascularization, 2020 - Elsevier
Intravascular dissemination of tumor cells is the accepted mechanism of cancer metastasis.
However, the field of angiotropism, pericyte mimicry (PM), and extravascular migratory …