Molecular biology of potyviruses

F Revers, JA García - Advances in virus research, 2015 - Elsevier
Potyvirus is the largest genus of plant viruses causing significant losses in a wide range of
crops. Potyviruses are aphid transmitted in a nonpersistent manner and some of them are …

Dissecting the molecular network of virus-plant interactions: the complex roles of host factors

A Wang - Annual review of phytopathology, 2015 - annualreviews.org
A successful infection by a plant virus results from the complex molecular interplay between
the host plant and the invading virus. Thus, dissecting the molecular network of virus-host …

Mimicking natural polymorphism in eIF4E by CRISPR‐Cas9 base editing is associated with resistance to potyviruses

A Bastet, D Zafirov, N Giovinazzo… - Plant Biotechnology …, 2019 - Wiley Online Library
In many crop species, natural variation in eIF 4E proteins confers resistance to potyviruses.
Gene editing offers new opportunities to transfer genetic resistance to crops that seem to …

Eukaryotic translation initiation factor 4E‐mediated recessive resistance to plant viruses and its utility in crop improvement

A Wang, S Krishnaswamy - Molecular plant pathology, 2012 - Wiley Online Library
The use of genetic resistance is considered to be the most effective and sustainable
approach to the control of plant pathogens. Although most of the known natural resistance …

Structural disorder in viral proteins

B Xue, D Blocquel, J Habchi, AV Uversky… - Chemical …, 2014 - ACS Publications
One of the core standards of biochemistry is that the function of a protein relies on its 3D
structure. This idea posits that all the information required for a protein to perform its …

Recessive resistance to plant viruses

V Truniger, MA Aranda - Advances in virus research, 2009 - Elsevier
About half of the∼ 200 known virus resistance genes in plants are recessively inherited,
suggesting that this form of resistance is more common for viruses than for other plant …

Natural variation and functional analyses provide evidence for co‐evolution between plant eIF4E and potyviral VPg

C Charron, M Nicolaï, JL Gallois, C Robaglia… - The Plant …, 2008 - Wiley Online Library
Amino acid substitutions in the eukaryotic translation initiation factor 4E (eIF4E) result in
recessive resistance to potyviruses in a range of plant species, including Capsicum spp …

Control of the eIF4E activity: structural insights and pharmacological implications

A Romagnoli, M D'Agostino, C Ardiccioni… - Cellular and Molecular …, 2021 - Springer
The central role of eukaryotic translation initiation factor 4E (eIF4E) in controlling mRNA
translation has been clearly assessed in the last decades. eIF4E function is essential for …

Signaling in induced resistance

JP Carr, MG Lewsey, P Palukaitis - Advances in virus research, 2010 - Elsevier
Induced mechanisms are by definition imperceptible or less active in uninfected, unstressed,
or untreated plants, but can be activated by pathogen infection, stress, or chemical treatment …

Sources of natural resistance to plant viruses: status and prospects

AJ Maule, C Caranta, MI Boulton - Molecular plant pathology, 2007 - Wiley Online Library
Globally, virus diseases are common in agricultural crops and have a major agronomic
impact. They are countered through the deployment of genetic resistance against the virus …