Mechanistic understanding of protein Corona formation around nanoparticles: old puzzles and new insights

K Nienhaus, GU Nienhaus - Small, 2023 - Wiley Online Library
Although a wide variety of nanoparticles (NPs) have been engineered for use as disease
markers or drug delivery agents, the number of nanomedicines in clinical use has hitherto …

Concepts and Approaches to Reduce or Avoid Protein Corona Formation on Nanoparticles: Challenges and Opportunities

M Barz, WJ Parak, R Zentel - Advanced Science, 2024 - Wiley Online Library
This review describes the formation of a protein corona (or its absence) on different classes
of nanoparticles, its basic principles, and its consequences for nanomedicine. For this …

The dynamics of PEG‐coated nanoparticles in concentrated protein solutions up to the molecular crowding range

F Otto, F Dallari, F Westermeier, DCF Wieland… - …, 2024 - Wiley Online Library
Polymer‐coated nanoparticles are widely studied in the context of nanomedicine and it is
therefore of utmost importance to understand not only how their structure but also how their …

Nano‐bio‐interface: Unleashing the Potential of Noble Nanometals

P Guo, Y Wang, H Cui, X Yao, G Guan… - Small Science, 2024 - Wiley Online Library
Engineered noble metal nanomaterials (NMN) possess adjustable optical, electrical, and
biocompatible properties that make them excellent tools for probing the nano‐bio‐interface …

Distinguishing Protein Corona from Nanoparticle Aggregate Formation in Complex Biological Media Using X-ray Photon Correlation Spectroscopy

CEP Silva, AS Picco, FE Galdino… - Nano Letters, 2024 - ACS Publications
In biological systems, nanoparticles interact with biomolecules, which may undergo protein
corona formation that can result in noncontrolled aggregation. Therefore, comprehending …

Recent advances in synchrotron scattering methods for probing the structure and dynamics of colloids

T Narayanan - Advances in Colloid and Interface Science, 2024 - Elsevier
Recent progress in synchrotron based X-ray scattering methods applied to colloid science is
reviewed. An important figure of merit of these techniques is that they enable in situ …

Electron Donor‐Specific Surface Interactions Promote the Photocatalytic Activity of Metal‐Semiconductor Nanohybrids

S Wengler‐Rust, YU Staechelin, H Lange, H Weller - Small, 2024 - Wiley Online Library
In the past two decades, the application of colloidal semiconductor‐metal nanoparticles
(NPs) as photocatalysts for the hydrogen generation from water has been extensively …

Dynamic X-ray Coherent Diffraction Analysis: Bridging the Time Scales between Imaging and Photon Correlation Spectroscopy

GN Hinsley, F Westermeier, B Wang, KH Ngoi… - Nano Letters, 2024 - ACS Publications
The advent of diffraction limited sources and developments in detector technology opens up
new possibilities for the study of materials in situ and operando. Coherent X-ray diffraction …

In situ aggregation and early states of gelation of gold nanoparticle dispersions

F Schulz, A Jain, F Dallari, V Markmann, F Lehmkühler - Soft Matter, 2024 - pubs.rsc.org
The aggregation and onset of gelation of PEGylated gold nanoparticles dispersed in a
glycerol–water mixture is studied by small-angle X-ray scattering and X-ray photon …

Probing the Cellular Fate of the Protein Corona around Nanoparticles with Nanofocused X-ray Fluorescence Imaging

M Skiba, G Guedes, D Karpov, N Feliu… - International Journal of …, 2023 - mdpi.com
X-ray fluorescence imaging (XRF-imaging) with subcellular resolution is used to study the
intracellular integrity of a protein corona that was pre-formed around gold nanoparticles …