GABA tone regulation and its cognitive functions in the brain
Abstract γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter released at
GABAergic synapses, mediating fast-acting phasic inhibition. Emerging lines of evidence …
GABAergic synapses, mediating fast-acting phasic inhibition. Emerging lines of evidence …
GABA and GABA receptors in the central nervous system and other organs
M Watanabe, K Maemura, K Kanbara… - International review of …, 2002 - Elsevier
γ-Aminobutyrate (GABA) is a major inhibitory neurotransmitter in the adult mammalian brain.
GABA is also considered to be a multifunctional molecule that has different situational …
GABA is also considered to be a multifunctional molecule that has different situational …
Murine features of neurogenesis in the human hippocampus across the lifespan from 0 to 100 years
R Knoth, I Singec, M Ditter, G Pantazis, P Capetian… - PloS one, 2010 - journals.plos.org
Background Essentially all knowledge about adult hippocampal neurogenesis in humans
still comes from one seminal study by Eriksson et al. in 1998, although several others have …
still comes from one seminal study by Eriksson et al. in 1998, although several others have …
BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex
Maturation of the visual cortex is influenced by visual experience during an early postnatal
period. The factors that regulate such a critical period remain unclear. We examined the …
period. The factors that regulate such a critical period remain unclear. We examined the …
Towards a better understanding of GABAergic remodeling in Alzheimer's disease
K Govindpani, B Calvo-Flores Guzmán… - International journal of …, 2017 - mdpi.com
γ-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the vertebrate brain.
In the past, there has been a major research drive focused on the dysfunction of the …
In the past, there has been a major research drive focused on the dysfunction of the …
The regulation of glutamic acid decarboxylases in GABA neurotransmission in the brain
SE Lee, Y Lee, GH Lee - Archives of pharmacal research, 2019 - Springer
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter that is required for
the control of synaptic excitation/inhibition and neural oscillation. GABA is synthesized by …
the control of synaptic excitation/inhibition and neural oscillation. GABA is synthesized by …
Two isoforms of glutamate decarboxylase: why?
JJ Soghomonian, DL Martin - Trends in pharmacological sciences, 1998 - cell.com
Adults express two isoforms of glutamate decarboxylase (GAD), GAD67 and GAD65, which
are encoded by different independently regulated genes, a situation that differs from that of …
are encoded by different independently regulated genes, a situation that differs from that of …
The concise guide to PHARMACOLOGY 2013/14: enzymes
SPH Alexander, HE Benson… - British Journal of …, 2013 - Wiley Online Library
Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …
Glutamic acid decarboxylase 65 and 67 kDa proteins are reduced in autistic parietal and cerebellar cortices
BACKGROUND: A limited number of reports have demonstrated abnormalities involving the
glutamate and gamma amino butyric acid systems in blood and platelets of subjects with …
glutamate and gamma amino butyric acid systems in blood and platelets of subjects with …
Neurobiological mechanisms of the onset of puberty in primates
EI Terasawa, DL Fernandez - Endocrine reviews, 2001 - academic.oup.com
An increase in pulsatile release of LHRH is essential for the onset of puberty. However, the
mechanism controlling the pubertal increase in LHRH release is still unclear. In primates the …
mechanism controlling the pubertal increase in LHRH release is still unclear. In primates the …