In many systems, microtubules contribute spatial information to cell morphogenesis, for
instance in cell migration and division. In rod-shaped fission yeast cells, microtubules control …

The localization, mass, and dynamics of microtubules are important in many processes.
Cells may actively monitor the state of their microtubules and respond to perturbation, but …

Abstract Effects not related with the inhibition of complex I of the mitochondrial electron
transport chain are studied in S. pombe, which lacks it. This study aims: First, the use of a …

In several cancer cell lines, depleting the microtubule (MT)‐destabilizing protein stathmin/
oncoprotein18 leads to a G2 cell cycle delay and apoptosis. These phenotypes are …

How cells regulate their size from one generation to the next has remained an enigma for
decades. Recently, a molecular mechanism that links cell size and cell cycle was proposed …

Schizosaccharomyces pombe delays entry into mitosis following G 2 microtubule damage.
This pathway is dependent on Rad26 ATRIP, the regulatory subunit of the Rad26 …

The conserved fission yeast protein Rad26ATRIP preserves genomic stability by occupying
central positions within DNA-structure checkpoint pathways. It is also required for proper …

The DNA damage response (DDR) ensures cellular survival by coordinating DNA repair
processes within the cell cycle to prevent accumulation of DNA damage. Improper function …

The DNA structure checkpoint protein Rad26 ATRIP is also required for an interphase
microtubule damage response. This checkpoint delays spindle pole body separation and …

Control of cell proliferation is greatly diminished in cancer cells. In order to understand how
to prevent the uncontrolled proliferation of cancer cells, it is first important to understand how …