As an anti-inflammatory alkaloid, nicotine plays dual roles in treating diseases. Here we
reviewed the anti-inflammatory and pro-inflammatory effects of nicotine on inflammatory …

The classical studies of nicotine by Langley at the turn of the 20th century introduced the
concept of a “receptive substance,” from which the idea of a “receptor” came to light …

This Opinion article discusses emerging evidence of direct contributions of nicotine to
cancer onset and growth. The list of cancers reportedly connected to nicotine is expanding …

Until recently, research on (S)-(-)-nicotine (1, hereafter simply nicotine) and nicotinic
acetylcholine receptors (nAChRs) emphasized two principal aspects. The first was the …

The molecular mechanisms of general anaesthetics have remained largely obscure since
their introduction into clinical practice just over 150 years ago. This review describes the …

ACh receptors sensitive to nicotine (nAChR) are present in human skin keratinocytes and in
bronchial epithelial cells. They are stimulated by ACh secreted by the same cells that …

The epithelial or endothelial cells that line the human bronchi and the aorta express nicotinic
acetylcholine receptors (nAChRs) of α3 subtypes. We report here that human bronchial …

Natural products that have both plant growth regulatory properties and pharmaceutical
properties are examined in this book. This is the first and most up-to-date text linking …

We demonstrated previously that human skin keratinocytes express acetylcholine receptors
(AChRs) sensitive to acetylcholine and nicotine, which regulate cell adhesion and motility …

In human skin both resident and transiently residing cells are part of the extra-or non-
neuronal cholinergic system, creating a highly complex and interconnected cosmos in which …