Follicle-stimulating hormone signaling is essential for the initiation and early stages of
spermatogenesis. Follicle-stimulating hormone receptor is exclusively expressed in Sertoli …

The testis is an important male reproductive organ, which ensures reproductive function via
the secretion of testosterone and the generation of spermatozoa. Testis development begins …

In order to reveal the complex mechanism governing the mitotic/meiotic switch in female
germ cells at epigenomic and genomic levels, we examined the chromatin accessibility …

Multiple RNA pathways are required to produce functional sperm. Here, we review RNA post-
transcriptional regulation during spermatogenesis with particular emphasis on the role of …

Spermatogenesis is a complex and dynamic process which is precisely controlledby genetic
and epigenetic factors. With the development of new technologies (eg, single-cell RNA …

Studies indicate that phthalates are endocrine disruptors affecting reproductive health. One
of the most commonly used phthalates, di-n-butyl phthalate (DBP), has been linked with …

Fertility and gamete reserves are maintained by asymmetric divisions of the germline stem
cells to produce new stem cells or daughters that differentiate as gametes. Before entering …

Spermatogenesis carries the task of precise intergenerational transmission of genetic
information from the paternal genome and involves complex developmental processes …

Human male reproductive development has a prolonged prepubertal period characterized
by juvenile quiescence of germ cells with immature spermatogonial stem cell (SSC) …

Control over gene expression is exerted, in multiple stages of spermatogenesis, at the post-
transcriptional level by RNA binding proteins (RBPs). We identify here an essential role in …