Coronaviruses (CoVs) are by far the largest group of known positive‐sense RNA viruses
having an extensive range of natural hosts. In the past few decades, newly evolved …

SARS-CoV-2 is a new beta coronavirus, similar to SARS-CoV-1, that emerged at the end of
2019 in the Hubei province of China. It is responsible for coronavirus disease 2019 (COVID …

Abstract Coronavirus disease 2019 (COVID-19) is a disease caused by infection with severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has resulted in a pandemic …

An excessive immune response contributes to SARS-CoV, MERS-CoV and SARS-CoV-2
pathogenesis and lethality, but the mechanism remains unclear. In this study, the N proteins …

The novel coronavirus disease COVID-19 originates in the lungs, but it may extend to other
organs, causing, in severe cases, multiorgan damage, including cardiac injury and acute …

Acute respiratory distress syndrome (ARDS) is immune-driven pathologies that are
observed in severe cases of severe acute respiratory syndrome coronavirus (SARS-CoV) …

Patients with coronavirus disease 2019 (COVID-19) present a wide range of acute clinical
manifestations affecting the lungs, liver, kidneys, and gut. Angiotensin-converting enzyme 2 …

For more than two decades, sepsis was defined as a microbial infection that produces fever
(or hypothermia), tachycardia, tachypnoea and blood leukocyte changes. Sepsis is now …

Excessive inflammatory responses contribute to the pathogenesis and lethality of highly
pathogenic human coronaviruses, but the underlying mechanism remains unclear. In this …

Background Complement pathway inhibition may provide benefit for severe acute
respiratory illnesses caused by viral infections such as COVID-19. We present results from a …