Spike timing dependent plasticity (STDP) is a phenomenon in which the precise timing of
spikes affects the sign and magnitude of changes in synaptic strength. STDP is often …

We review biophysical models of synaptic plasticity, with a focus on spike-timing dependent
plasticity (STDP). The common property of the discussed models is that synaptic changes …

The calcium/calmodulin-dependent protein kinase II (CaMKII) plays a key role in the
induction of long-term postsynaptic modifications following calcium entry. Experiments …

Glutamatergic gliotransmission, that is, the release of glutamate from perisynaptic astrocyte
processes in an activity‐dependent manner, has emerged as a potentially crucial signaling …

Synaptic efficacy is subjected to activity-dependent changes on short-and long time scales.
While short-term changes decay over minutes, long-term modifications last from hours up to …

The NMDAR-dependent synaptic plasticity is thought to mediate several forms of learning,
and can be induced by spike trains containing a small number of spikes occurring with …

More than a hundred biochemical species, activated by neurotransmitters binding to
transmembrane receptors, are important in long-term potentiation (LTP) and long-term …

Discovering the rules of synaptic plasticity is an important step for understanding brain
learning. Existing plasticity models are either (1) top-down and interpretable, but not flexible …

Hebbian learning in cortical networks during development and adulthood relies on the
presence of a mechanism to detect correlation between the presynaptic and the …

Neuroplasticity refers to functional and structural changes in brain regions in response to
healthy and pathological activity. Activity dependent plasticity induced by epileptic activity …