The lipoprotein HDL has two important roles: first, it promotes reverse cholesterol transport,
and second, it modulates inflammation. Epidemiological studies show that HDL-cholesterol …

Atherosclerosis, the pathological basis of most cardiovascular disease (CVD), is closely
associated with cholesterol accumulation in the arterial intima. Excessive cholesterol is …

Due to many special characteristics, zinc oxide nanoparticles (ZnO NPs) are widely used all
over the world, leading to their wide distribution in the environment. However, the toxicities …

The use of nanotechnology for medical purposes—nanomedicine—has grown exponentially
over the past few decades. This is exemplified by the US Food and Drug Administration's …

High Density Lipoprotein (HDL) particles, beyond serving as lipid transporters and playing a
key role in reverse cholesterol transport, carry a highly variable number of proteins, micro …

Objective: HDL (high-density lipoprotein) infusion reduces atherosclerosis in animal models
and is being evaluated as a treatment in humans. Studies have shown either anti-or …

Atherosclerosis is a complex disease in which many processes contribute to lesion
development. Yet, it is well accepted that high serum levels of low‐density lipoproteins (LDL) …

Studies have shown a reduction in plaque volume and change in plaque ultrasound
characteristics after 4 infusions of reconstituted high-density lipoprotein (rHDL). Whether …

The underlying role of inflammation in atherosclerosis has been characterized. However,
current treatment of coronary artery disease (CAD) predominantly consists of targeted …

Objective—Preclinical and clinical studies have shown beneficial effects of infusions of
apolipoprotein AI (ApoA-I) on atherosclerosis. ApoA-I is also a target for myeloperoxidase …