Marrow adipocytes, collectively termed marrow adipose tissue (MAT), reside in the bone
marrow in close contact to bone cells and haematopoietic cells. Marrow adipocytes arise …

Most adipocytes exist in discrete depots throughout the body, notably in well-defined white
and brown adipose tissues. However, adipocytes also reside within specialized niches, of …

Skeletal stem cells (SSCs) that are the major source of osteoblasts and adipocytes in adult
bone marrow express leptin receptor (LepR). To test whether LepR regulates SSC function …

Endocrine complications, including diabetes and metabolic syndrome, are highly prevalent
in childhood cancer survivors. These metabolic derangements may contribute to survivors' …

Monocytes play a key role in the development of metabolic syndrome, and especially
obesity. Given the complex features of their development from progenitor cells, whose …

Following the increased awareness about the central role of the pediatric age in building
bone for life, clinicians face more than ever the necessity of assessing bone health in …

The bone marrow is home to well-balanced normal hematopoiesis, but also the stage of
leukemia's crime. Marrow adipose tissue (MAT) is a unique and versatile component of the …

The relationship between fat, bone and systemic metabolism is a growing area of scientific
interest. Marrow adipose tissue is a well-recognized component of the bone marrow milieu …

Metabolic syndrome (MetS) is a constellation of cardiovascular risk factors that increases the
risk of cardiovascular disease, diabetes mellitus and all cause mortality. Long-term survivors …

Bone strength is affected not only by bone mineral density (BMD) and bone
microarchitecture but also its microenvironment. Recent studies have focused on the role of …