Brain-derived neurotrophic factor (BDNF) promotes neuroprotection and neuroregeneration.
In animal models of Parkinson's disease (PD), BDNF enhances the survival of dopaminergic …

Background & Objective: A number of neuropsychiatric disorders, including Parkinson's
disease, schizophrenia, attention deficit hyperactivity disorder, and, to some extent …

Glial-cell line derived neurotrophic factor (GDNF) bound to its co-receptor GFRα1 stimulates
the RET receptor tyrosine kinase, promoting neuronal survival and neuroprotection. The …

Chrysin is a natural flavonoid which is found in bee propolis, honey and various plants, and
neuroprotective effect of chrysin in mice was previously demonstrated by our group …

The Glial cell line-derived neurotrophic Family Ligands (GFL) are soluble neurotrophic
factors that are required for development of multiple human tissues, but which are also …

Presynaptic increase in striatal dopamine is the primary dopaminergic abnormality in
schizophrenia, but the underlying mechanisms are not understood. Here, we hypothesized …

The present study investigated the possible relationship between pro-inflammatory
cytokines and programmed nigral neuronal death in rotenone model of Parkinson's disease …

Sertoli cells regulate male germ cell proliferation and differentiation and are a critical
component of the spermatogonial stem cell (SSC) niche, where homeostasis is maintained …

Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons from the
substantia nigra (SN) that project to the dorsal striatum (caudate-putamen). To better …

The increase in presynaptic striatal dopamine is the main dopaminergic abnormality in
schizophrenia (SCZ). SCZ is primarily treated by modulating the activity of monoamine …