Ultra‐high dose rate dosimetry: challenges and opportunities for FLASH radiation therapy

F Romano, C Bailat, PG Jorge, MLF Lerch… - Medical …, 2022 - Wiley Online Library
The clinical translation of FLASH radiotherapy (RT) requires challenges related to dosimetry
and beam monitoring of ultra‐high dose rate (UHDR) beams to be addressed. Detectors …

A review on radiochromic film dosimetry for dose verification in high energy photon beams

T Santos, T Ventura, M do Carmo Lopes - Radiation Physics and Chemistry, 2021 - Elsevier
A dosimetry system composed by Gafchromic™ EBT films and a flatbed document scanner
is a valuable tool for patient-specific quality assurance (QA) of complex external beam …

Feasibility of proton FLASH irradiation using a synchrocyclotron for preclinical studies

A Darafsheh, Y Hao, T Zwart, M Wagner… - Medical …, 2020 - Wiley Online Library
Purpose It has been recently shown that radiotherapy at ultrahigh dose rates (> 40 Gy/s,
FLASH) has a potential advantage in sparing healthy organs compared to that at …

Electron FLASH delivery at treatment room isocenter for efficient reversible conversion of a clinical LINAC

M Rahman, MR Ashraf, R Zhang, P Bruza… - International Journal of …, 2021 - Elsevier
Purpose In this study, procedures were developed to achieve efficient reversible conversion
of a clinical linear accelerator (LINAC) and deliver ultrahigh-dose-rate (UHDR) electron or …

Spread‐out Bragg peak proton FLASH irradiation using a clinical synchrocyclotron: proof of concept and ion chamber characterization

A Darafsheh, Y Hao, X Zhao, T Zwart… - Medical …, 2021 - Wiley Online Library
Purpose The purpose of this work is to (a) demonstrate the feasibility of delivering a spread‐
out Bragg peak (SOBP) proton beam in ultra‐high dose rate (FLASH) using a proton therapy …

Characterization and practical applications of a novel plastic scintillator for online dosimetry for an ultrahigh dose rate (FLASH)

Y Poirier, J Xu, S Mossahebi… - Medical …, 2022 - Wiley Online Library
Purpose Although flash radiation therapy (FLASH‐RT) is a promising novel technique that
has the potential to achieve a better therapeutic ratio between tumor control and normal …

Comparative study on measurements of radiochromic films using portable colorimeters

H Yasuda, S Morioka - Scientific Reports, 2024 - nature.com
The recently proposed method for on-site radiation dosimetry by a combination of
radiochromic film and portable colorimeter was tested for six combinations of two popular …

Radiation shielding and safety implications following linac conversion to an electron FLASH‐RT unit

Y Poirier, S Mossahebi, SJ Becker, B Koger… - Medical …, 2021 - Wiley Online Library
Purpose Due to their finite range, electrons are typically ignored when calculating shielding
requirements in megavoltage energy linear accelerator vaults. However, the assumption that …

Characterization of a diode dosimeter for UHDR FLASH radiotherapy

M Rahman, J Kozelka, J Hildreth, A Schönfeld… - Medical …, 2023 - Wiley Online Library
Background Ultra‐high dose rate (UHDR) FLASH beams typically deliver dose at rates of>
40 Gy/sec. Characterization of these beams with respect to dose, mean dose rate, and dose …

Application of a portable colorimeter for reading a radiochromic film for on-site dosimetry

H Yasuda, H Yoshida - Applied Sciences, 2023 - mdpi.com
Featured Application The present study has demonstrated that simple, accurate on-site
dosimetry with a radiochromic film (Gafchromic EBT-XD) can be achieved by using a …