Bivalves present the largest and most diversified repertoire of toll-like receptors in the animal kingdom, suggesting broad-spectrum pathogen recognition in marine …

A Saco, B Novoa, S Greco, M Gerdol… - Molecular Biology and …, 2023 - academic.oup.com
Toll-like receptors (TLRs) are the most widespread class of membrane-bound innate
immune receptors, responsible of specific pathogen recognition and production of immune …

A genomic and transcriptomic analysis of the C-Type lectin Gene Family reveals highly expanded and Diversified repertoires in Bivalves

A Saco, H Suárez, B Novoa, A Figueras - Marine Drugs, 2023 - mdpi.com
C-type lectins belong to a widely conserved family of lectins characterized in Metazoa. They
show important functional diversity and immune implications, mainly as pathogen …

Chromosome‐level reference genome for European flat oyster (Ostrea edulis L.)

MK Gundappa, C Peñaloza, T Regan… - Evolutionary …, 2022 - Wiley Online Library
Abstract The European flat oyster (Ostrea edulis L.) is a bivalve naturally distributed across
Europe, which was an integral part of human diets for centuries, until anthropogenic …

Multiple and diversified transposon lineages contribute to early and recent bivalve genome evolution

J Martelossi, F Nicolini, S Subacchi, D Pasquale… - BMC biology, 2023 - Springer
Abstract Background Transposable elements (TEs) can represent one of the major sources
of genomic variation across eukaryotes, providing novel raw materials for species …

[HTML][HTML] Mussel antiviral transcriptome response and elimination of viral haemorrhagic septicaemia virus (VHSV)

A Saco, M Rey-Campos, B Novoa… - Fish & Shellfish …, 2023 - Elsevier
As filter-feeding bivalves, mussels have been traditionally studied as possible vectors of
different bacterial or viral pathogens. The absence of a known viral pathogen in these …

Pooled resequencing of larvae and adults reveals genomic variations associated with Ostreid herpesvirus 1 resistance in the Pacific oyster Crassostrea gigas

S Yao, L Li, X Guan, Y He, A Jouaux, F Xu… - Frontiers in …, 2022 - frontiersin.org
The Ostreid herpesvirus 1 (OsHV-1) is a lethal pathogen of the Pacific oyster (Crassostrea
gigas), an important aquaculture species. To understand the genetic architecture of the …

[HTML][HTML] Gene presence/absence variation in Mytilus galloprovincialis and its implications in gene expression and adaptation

A Saco, M Rey-Campos, C Gallardo-Escárate… - Iscience, 2023 - cell.com
Presence/absence variation (PAV) is a well-known phenomenon in prokaryotes that was
described for the first time in bivalves in 2020 in Mytilus galloprovincialis. The objective of …

The chromosome level genome assembly of the Asian green mussel, Perna viridis

S Sukumaran, VG Vysakh, W Sebastian… - Scientific Data, 2024 - nature.com
Abstract The Asian green mussel, Perna viridis is an important aquaculture species in the
family Mytilidae contributing substantially to molluscan aquaculture. We generated a high …

Reproductive toxicity induced by benzo[a]pyrene exposure: first exploration highlighting the multi-stage molecular mechanism in female scallop Chlamys farreri

R Xu, L Pan, Y Zhou, Z Gao, J Miao, Y Yang… - … Science and Pollution …, 2022 - Springer
Reproductive toxicity induced by benzo [a] pyrene (B [a] P) exposure has received great
ecotoxicological concerns. However, huge gaps on the molecular mechanism still exist in …

[HTML][HTML] Tracing the evolution of tissue inhibitor of metalloproteinases in Metazoa with the Pteria penguin genome

CY Ma, Y Chen, X Zhan, YW Dong - Iscience, 2024 - cell.com
Tissue inhibitors of metalloproteinase (TIMPs) play a pivotal role in regulating extracellular
matrix (ECM) dynamics and have been extensively studied in vertebrates. However …