Adequate supply of blood and structural and functional integrity of blood vessels are key to
normal brain functioning. On the other hand, cerebral blood flow shortfalls and blood–brain …

Cerebral blood flow (CBF) regulation is essential for normal brain function. The mammalian
brain has evolved a unique mechanism for CBF control known as neurovascular coupling …

Research utilizing magnetic resonance imaging (MRI) has been crucial to the understanding
of the neuropathological mechanisms behind and clinical identification of Alzheimer's …

Alzheimer's disease causes a progressive dementia that currently affects over 35 million
individuals worldwide and is expected to affect 115 million by 2050 (ref. 1). There are no …

Introduction: The neuropsychological profile of people with mild cognitive impairment (MCI)
and Alzheimer's disease (AD) dementia includes a history of decline in memory and other …

Age-related cognitive changes often include difficulties in retrieving memories, particularly
those that rely on personal experiences within their temporal and spatial contexts (ie …

Imaging has played a variety of roles in the study of Alzheimer disease (AD) over the past
four decades. Initially, computed tomography (CT) and then magnetic resonance imaging …

A New York Times Notable Book: A psychologist's “gripping and thought-provoking” look at
how and why our brains sometimes fail us (Steven Pinker, author of How the Mind Works). In …

When people talk, they gesture. Gesture is a fundamental component of language that
contributes meaningful and unique information to a spoken message and reflects the …

Pattern separation, the ability to independently represent and store similar experiences, is a
crucial facet of episodic memory. Growing evidence suggests that the hippocampus …