Asthma is a heterogeneous lung disease with variable phenotypes (clinical presentations)
and distinctive endotypes (mechanisms). Over the last decade, considerable efforts have …

Mast cells are important components of the immune system, and they perform pro-
inflammatory as well as anti-inflammatory roles in the complex process of immune regulation …

Airway remodeling in asthma: update on mechanisms and therap... : Current Opinion in
Pulmonary Medicine Airway remodeling in asthma: update on mechanisms and therapeutic …

Improving the lung function after experimental allergen challenge by blocking of mast cell
(MC) mediators and the capability of MC mediators (including histamine, prostaglandin (PG) …

Asthma is the most common chronic lung disease in children and young adults worldwide.
Airway remodelling (including increased fibroblasts and myofibroblasts in airway walls due …

Background Mast cells (MCs) and basophils are important in asthma pathophysiology,
however direct measurement is difficult, and clinical and inflammatory associations in severe …

Background and objective The pathology of asthma is characterized by airway inflammation
(granulocytic (GA) or paucigranulocytic (PGA)) and remodelling of airway structures …

Mast cells (MCs) are granular cells of the innate immune system which develop from
CD34+/CD117+ progenitors and play a role in orchestrating adaptive immune responses …

The proliferation and migration of airway smooth muscle cells (ASMCs) plays an important
role in asthma. Recently, the function of long noncoding RNA (lncRNA) in the ASMCs has …

Background Antigen‐specific memory B cells play a key role in the induction of
desensitization and remission to food allergens in oral immunotherapy and in the …