Background Gastric motility disorders, which include both functional and organic etiologies,
are highly prevalent. However, there remains a critical lack of objective biomarkers to guide …

Gastric peristalsis is critically dependent on an underlying electrical conduction system.
Recent years have witnessed substantial progress in clarifying the operations of this system …

Mathematical and computational modeling of the stomach is an emerging field of
biomechanics where several complex phenomena, such as gastric electrophysiology, fluid …

Food transport through different sections of the gastrointestinal tract for the purposes of
digestion and waste removal is an essential physiological function for life. Mechanical and …

High-resolution (HR) mapping has been used to study gastric slow-wave activation;
however, the specific characteristics of antral electrophysiology remain poorly defined. This …

Gastric pacing and stimulation strategies were first proposed in the 1960s to treat motility
disorders. However, there has been relatively limited clinical translation of these techniques …

Over the last two decades, high-resolution (HR) mapping has emerged as a powerful
technique to study normal and abnormal bioelectrical events in the gastrointestinal (GI) tract …

Gastrointestinal (GI) motility is regulated in part by electrophysiological events called slow
waves, which are generated by the interstitial cells of Cajal (ICC). Slow waves propagate by …

Routine screening and accurate diagnosis of chronic gastrointestinal motility disorders
represent a significant problem in current clinical practice. The electrogastrography (EGG) …

A key discovery in gastrointestinal motility has been the central role played by interstitial
cells of Cajal (ICC) in generating electrical slow waves that coordinate contractions …