[HTML][HTML] Cataract in diabetes mellitus

H Kiziltoprak, K Tekin, M Inanc… - World journal of …, 2019 - ncbi.nlm.nih.gov
Diabetes mellitus (DM) is a chronic systemic disease that has increases in prevalence over
time. DM can affect all ocular structures, with cataract being the most common ocular …

Epidemiology of ocular manifestations in autoimmune disease

K Glover, D Mishra, TRR Singh - Frontiers in immunology, 2021 - frontiersin.org
The global prevalence of autoimmune diseases is increasing. As a result, ocular
complications, ranging from minor symptoms to sight-threatening scenarios, associated with …

[HTML][HTML] ISPAD Clinical Practice Consensus Guidelines 2018: Microvascular and macrovascular complications in children and adolescents

KC Donaghue, ML Marcovecchio, RP Wadwa… - Pediatric …, 2018 - ncbi.nlm.nih.gov
The long-term vascular complications of diabetes include nephropathy, retinopathy,
neuropathy, and macrovascular disease. The outcomes are:• renal failure and hypertension …

[PDF][PDF] ISPAD clinical practice consensus guidelines 2022: microvascular and macrovascular complications in children and adolescents with diabetes

P Bjornstad, A Dart, KC Donaghue, A Dost… - 2022 - deepblue.lib.umich.edu
The long-term vascular complications of diabetes include diabetic kidney disease (DKD),
retinopathy, neuropathy, and macrovascular disease. The outcomes are:• kidney failure and …

[PDF][PDF] Microvascular and macrovascular complications in children and adolescents.

KC Donaghue, RP Wadwa, LA Dimeglio, TY Wong… - Pediatric diabetes, 2014 - bnsde.org
The long-term vascular complications of diabetes include retinopathy, nephropathy,
neuropathy, and macrovascular disease. The outcomes are:• visual impairment and …

LncRNA KCNQ1OT1 knockdown inhibits viability, migration and epithelial-mesenchymal transition in human lens epithelial cells via miR-26a-5p/ITGAV/TGF-beta …

J Liu, Y Dong, Y Wen, L Shi, Z Zhu, G Ke… - Experimental eye research, 2020 - Elsevier
Background Long noncoding RNA potassium voltage-gated channel subfamily Q member 1
opposite strand/antisense transcript 1 (KCNQ1OT1) takes part in diabetic cataract …

High risk of early cataracts in young type 1 diabetes group: a nationwide cohort study

WL Lu, PC Shen, CH Lee, YT Su… - International Journal of …, 2020 - Wiley Online Library
Background. Chronic hyperglycemia in type 1 diabetes (T1D) patients results in ocular
problems over time, but only a few studies emphasized on cataracts. Aim. To evaluate the …

Chrysin reduces oxidative stress but does not affect polyol pathway in the lenses of type 1 diabetic rats

W Wojnar, M Zych, S Borymski, I Kaczmarczyk-Sedlak - Antioxidants, 2020 - mdpi.com
Prolonged hyperglycemia is one of the main causes of reactive oxygen species and free
radicals generation in diabetes which may affect various organs, including the eye …

Pathophysiology, etiology, epidemiology of type 1 diabetes and computational approaches for immune targets and therapy

B Dariya, G Chalikonda, G Srivani… - Critical Reviews™ in …, 2019 - dl.begellhouse.com
Autoimmune diseases occur when the body's natural defense system fails to differentiate its
own cells from the foreign cells and mistakenly attacks the healthy cells. Among the …

[HTML][HTML] LncRNA GAS5 regulates migration and epithelial-to-mesenchymal transition in lens epithelial cells via the miR-204-3p/TGFBR1 axis

X Li, M Sun, A Cheng, G Zheng - Laboratory Investigation, 2022 - Elsevier
Diabetic cataract (DC) is a major ocular complication secondary to diabetes mellitus. The
epithelial-mesenchymal transition (EMT) of lens epithelial cells (LECs) is an important event …