Heart disease is the leading cause of death worldwide. Despite decades of research, most
heart pathologies have limited treatments, and often the only curative approach is heart …

Every animal grows from a single fertilized egg into an intricate network of cell types and
organ systems. This process is captured in a lineage tree: a diagram of every cell's ancestry …

Heart failure causes significant morbidity and mortality worldwide. The understanding of
heart failure pathomechanisms and options for treatment remain incomplete. Zebrafish has …

Since its discovery 150 years ago, the neural crest has intrigued investigators owing to its
remarkable developmental potential and extensive migratory ability. Cell lineage analysis …

Cardiac neural crest cells contribute to important portions of the cardiovascular system
including the aorticopulmonary septum and cardiac ganglion. Using replication incompetent …

Cardiac neural crest cells (cNCCs) are a migratory cell population that stem from the cranial
portion of the neural tube. They undergo epithelial-to-mesenchymal transition and migrate …

Glial cells are essential for functionality of the nervous system. Growing evidence
underscores the importance of astrocytes; however, analogous astroglia in peripheral …

Pacific herring (Clupea pallasii), a cornerstone of marine food webs, generally spawn on
marine macroalgae in shallow nearshore areas that are disproportionately at risk from oil …

In humans, myocardial infarction results in ventricular remodeling, progressing ultimately to
cardiac failure, one of the leading causes of death worldwide. In contrast to the adult …

Contemporary cardiac injury models in zebrafish larvae include cryoinjury, laser ablation,
pharmacological treatment and cardiac dysfunction mutations. Although effective in …