Summary our review will help clinicians to properly integrate the available diagnostic
modalities for the assessment of SSc-pHI. The ultimate goal is to propose a feasible …

Introduction Cardiac involvement is common in systemic sclerosis occurring in up to 80% of
patients. Primary myocardial dysfunction results from impairment of coronary microvascular …

Right ventricular (RV) function is important for clinical status and outcomes in children and
adults with congenital heart disease (CHD). In the normal RV, longitudinal systolic function …

Abstract Background Systemic sclerosis (SSc) heart involvement (SHI) is a leading cause of
SSc-associated mortality and once clinically overt, carries a very poor prognosis. There …

Systemic sclerosis is a multisystemic disease for which the heart can be affected leading to
cardiac complications and mortality. Up to 80% of patients with systemic sclerosis have …

Aims Cardiac involvement in patients with systemic sclerosis (SSc) is frequent and
represents a negative prognostic factor. Recent studies have described subclinical heart …

Objectives Cardiac involvement in patients with systemic sclerosis (SSc) is associated with
poor prognosis. Early detection of myocardial impairment is essential for treatment. The …

Background Cardiac involvement is a major cause of death in SSc, while early detection
remains a challenge. Objectives The purpose of this study was to investigate the prevalence …

Systemic sclerosis (SSc) is a complex connective tissue disease with multiple clinical and
subclinical cardiac manifestations. SSc can affect most structural components of the heart …

Background: Vascular dysfunction and its concomitant multi-organ involvement, including
cardiac involvement, affects prognosis in systemic sclerosis (SSc) patients. Regular exercise …