Molecular genetic variation of animals and plants under domestication
L Andersson, M Purugganan - Proceedings of the National …, 2022 - National Acad Sciences
Domesticated plants and animals played crucial roles as models for evolutionary change by
means of natural selection and for establishing the rules of inheritance, originally proposed …
means of natural selection and for establishing the rules of inheritance, originally proposed …
Tutorial: a statistical genetics guide to identifying HLA alleles driving complex disease
The human leukocyte antigen (HLA) locus is associated with more complex diseases than
any other locus in the human genome. In many diseases, HLA explains more heritability …
any other locus in the human genome. In many diseases, HLA explains more heritability …
Joint analysis of phenotype-effect-generation identifies loci associated with grain quality traits in rice hybrids
L Li, X Zheng, J Wang, X Zhang, X He, L Xiong… - Nature …, 2023 - nature.com
Genetic improvement of grain quality is more challenging in hybrid rice than in inbred rice
due to additional nonadditive effects such as dominance. Here, we describe a pipeline …
due to additional nonadditive effects such as dominance. Here, we describe a pipeline …
Genetic variation in histone modifications and gene expression identifies regulatory variants in the mammary gland of cattle
Background Causal variants for complex traits, such as eQTL are often found in non-coding
regions of the genome, where they are hypothesised to influence phenotypes by regulating …
regions of the genome, where they are hypothesised to influence phenotypes by regulating …
[HTML][HTML] Invited review: Good practices in genome-wide association studies to identify candidate sequence variants in dairy cattle
Genotype data from dairy cattle selection programs have greatly facilitated GWAS to identify
variants related to economic traits. Results can enhance the accuracy of genomic prediction …
variants related to economic traits. Results can enhance the accuracy of genomic prediction …
[HTML][HTML] Comparison of the genetic characteristics of directly measured and Fourier-transform mid-infrared-predicted bovine milk fatty acids and proteins
Fourier-transform mid-infrared (FT-MIR) spectroscopy is a high-throughput and inexpensive
methodology used to evaluate concentrations of fat and protein in dairy cattle milk samples …
methodology used to evaluate concentrations of fat and protein in dairy cattle milk samples …
Gene expression and RNA splicing explain large proportions of the heritability for complex traits in cattle
Many quantitative trait loci (QTLs) are in non-coding regions. Therefore, QTLs are assumed
to affect gene regulation. Gene expression and RNA splicing are primary steps of …
to affect gene regulation. Gene expression and RNA splicing are primary steps of …
Four novel candidate causal variants for deficient homozygous haplotypes in Holstein cattle
IM Häfliger, M Spengeler, FR Seefried… - Scientific reports, 2022 - nature.com
Mendelian variants can determine both insemination success and neonatal survival and
thus influence fertility and rearing success of cattle. We present 24 deficient homozygous …
thus influence fertility and rearing success of cattle. We present 24 deficient homozygous …
Massive detection of cryptic recessive genetic defects in dairy cattle mining millions of life histories
F Besnard, A Guintard, C Grohs, L Guzylack-Piriou… - Genome Biology, 2024 - Springer
Background Dairy cattle breeds are populations of limited effective size, subject to recurrent
outbreaks of recessive defects that are commonly studied using positional cloning. However …
outbreaks of recessive defects that are commonly studied using positional cloning. However …
Sequence-based genome-wide association study of individual milk mid-infrared wavenumbers in mixed-breed dairy cattle
Background Fourier-transform mid-infrared (FT-MIR) spectroscopy provides a high-
throughput and inexpensive method for predicting milk composition and other novel traits …
throughput and inexpensive method for predicting milk composition and other novel traits …