Heterogeneity of patients with intermediate (BCLC B) Hepatocellular Carcinoma: proposal for a subclassification to facilitate treatment decisions

L Bolondi, A Burroughs, JF Dufour… - Seminars in liver …, 2012 - thieme-connect.com
The intermediate stage of hepatocellular carcinoma (HCC) comprises a highly
heterogeneous patient population and therefore poses unique challenges for therapeutic …

[HTML][HTML] Hepatocellular carcinoma: From diagnosis to treatment

A Waghray, AR Murali, KVN Menon - World journal of hepatology, 2015 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the sixth most prevalent malignancy worldwide and is a
rising cause of cancer related mortality. Risk factors for HCC are well documented and …

US-triggered microbubble destruction for augmenting hepatocellular carcinoma response to transarterial radioembolization: a randomized pilot clinical trial

JR Eisenbrey, F Forsberg, CE Wessner, LJ Delaney… - Radiology, 2021 - pubs.rsna.org
Background US contrast agents are gas-filled microbubbles (MBs) that can be locally
destroyed by using external US. Among other bioeffects, US-triggered MB destruction, also …

Targeted radionuclide therapy-an overview

A Dash, F F.(Russ) Knapp… - Current …, 2013 - benthamdirect.com
Radionuclide therapy (RNT) based on the concept of delivering cytotoxic levels of radiation
to disease sites is one of the rapidly growing fields of nuclear medicine. Unlike conventional …

Contrast-enhanced ultrasound (CEUS) in HCC diagnosis and assessment of tumor response to locoregional therapies

JR Eisenbrey, H Gabriel, E Savsani, A Lyshchik - Abdominal Radiology, 2021 - Springer
Hepatocellular carcinoma (HCC) is a global problem constituting the second leading cause
of cancer deaths worldwide, thereby necessitating an accurate and cost-effective solution for …

Alantolactone induces apoptosis in HepG2 cells through GSH depletion, inhibition of STAT3 activation, and mitochondrial dysfunction

M Khan, T Li, MK Ahmad Khan, A Rasul… - BioMed research …, 2013 - Wiley Online Library
Signal transducer and activator of transcription 3 (STAT3) constitutively expresses in human
liver cancer cells and has been implicated in apoptosis resistance and tumorigenesis …

Boron clusters (ferrabisdicarbollides) shaping the future as radiosensitizers for multimodal (chemo/radio/PBFR) therapy of glioblastoma

M Nuez-Martínez, M Queralt-Martín… - Journal of Materials …, 2022 - pubs.rsc.org
Glioblastoma multiforme (GBM) is the most common and fatal primary brain tumor, and is
highly resistant to conventional radiotherapy and chemotherapy. Therefore, the …

Hispidulin induces apoptosis through mitochondrial dysfunction and inhibition of P13k/Akt signalling pathway in HepG2 cancer cells

H Gao, H Wang, J Peng - Cell biochemistry and biophysics, 2014 - Springer
Hispidulin is a flavonoid compound which is an active ingredient in a number of traditional
Chinese medicinal herbs. However, it's therapeutic activity remains poorly understood. The …

Highly tumor-specific and long-acting iodine-131 microbeads for enhanced treatment of hepatocellular carcinoma with low-dose radio-chemoembolization

Y Qian, Q Liu, P Li, Y Han, J Zhang, J Xu, J Sun, A Wu… - ACS …, 2021 - ACS Publications
Transarterial radioembolization (TARE) is considered the standard treatment for
intermediate-stage hepatocellular carcinoma (HCC). Iodine-131 (131I)-labeled lipiodol …

Radionuclide‐Labeled Microspheres for Radio‐Immunotherapy of Hepatocellular Carcinoma

S Yang, C Mu, T Liu, P Pei, W Shen… - Advanced …, 2023 - Wiley Online Library
Brachytherapy, including radioactive seed implantation (RSI) and transarterial radiation
therapy embolization (TARE), is an important treatment modality for advanced …