Modifiable risk and protective factors for boosting brain and cognitive development and
preventing neurodegeneration and cognitive decline are embraced in neuroimaging …

Despite decades of intense research, disease-modifying therapeutic approaches for
Alzheimer's disease (AD) are still very much needed. Apart from the extensively analyzed …

Understanding the causes of Alzheimer's disease and related dementias remains a
challenge. Observational studies investigating dementia risk factors are limited by the …

Background and objectives Observational studies have demonstrated a significant
association between socio-economic status (SES) and Alzheimer's disease (AD) …

A correlation between gut microbiota and brain structure, referring to as a component of the
gut–brain axis, has been observed in observational studies. However, the causality of this …

Purpose This study aimed to evaluate the use of serum neurofilament light chain (NfL) and
glial fibrillary acidic protein (GFAP) in the diagnosis of Alzheimer's disease (AD) and the …

Previous studies have identified metabolites as biomarkers or potential therapeutic targets
for traumatic brain injury (TBI). However, the causal association between them remains …

Objective This study is aim to explore the causal relationship between anxiety, depression,
neuroticism, and Meniere's disease (MD). Study Design Two‐sample bidirectional …

Alzheimer's disease and its comorbidities pose a heavy disease burden globally, and its
treatment remains a major challenge. Identifying the protective and risk factors for …

Previous observational investigations suggest that structural and diffusion imaging-derived
phenotypes (IDPs) are associated with major neurodegenerative diseases; however …