Multi‐Omics Factor Analysis—a framework for unsupervised integration of multi‐omics data sets
Multi‐omics studies promise the improved characterization of biological processes across
molecular layers. However, methods for the unsupervised integration of the resulting …
molecular layers. However, methods for the unsupervised integration of the resulting …
[HTML][HTML] mixOmics: An R package for 'omics feature selection and multiple data integration
The advent of high throughput technologies has led to a wealth of publicly available 'omics
data coming from different sources, such as transcriptomics, proteomics, metabolomics …
data coming from different sources, such as transcriptomics, proteomics, metabolomics …
[HTML][HTML] An integrated understanding of the rapid metabolic benefits of a carbohydrate-restricted diet on hepatic steatosis in humans
A carbohydrate-restricted diet is a widely recommended intervention for non-alcoholic fatty
liver disease (NAFLD), but a systematic perspective on the multiple benefits of this diet is …
liver disease (NAFLD), but a systematic perspective on the multiple benefits of this diet is …
Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy
MS Ghaemi, DB DiGiulio, K Contrepois… - …, 2019 - academic.oup.com
Motivation Multiple biological clocks govern a healthy pregnancy. These biological
mechanisms produce immunologic, metabolomic, proteomic, genomic and microbiomic …
mechanisms produce immunologic, metabolomic, proteomic, genomic and microbiomic …
Reprogramming of lipid metabolism in hepatocellular carcinoma resulting in downregulation of phosphatidylcholines used as potential markers for diagnosis and …
K Li, W Shi, Y Song, L Qin, C Zang, T Mei… - Expert Review of …, 2023 - Taylor & Francis
Background Aberrant methylation and metabolic perturbations may deepen our
understanding of hepatocarcinogenesis and help identify novel biomarkers for diagnosing …
understanding of hepatocarcinogenesis and help identify novel biomarkers for diagnosing …
[HTML][HTML] Dynamic molecular changes during the first week of human life follow a robust developmental trajectory
Abstract Systems biology can unravel complex biology but has not been extensively applied
to human newborns, a group highly vulnerable to a wide range of diseases. We optimized …
to human newborns, a group highly vulnerable to a wide range of diseases. We optimized …
[HTML][HTML] Proteomic and metaproteomic approaches to understand host–microbe interactions
The human body is composed not only of human cells but is occupied by bacteria, archaea,
fungi, and viruses; this ensemble of organisms (microbiota) and their expressed genes are …
fungi, and viruses; this ensemble of organisms (microbiota) and their expressed genes are …
Multi-omics integration—a comparison of unsupervised clustering methodologies
With the recent developments in the field of multi-omics integration, the interest in factors
such as data preprocessing, choice of the integration method and the number of different …
such as data preprocessing, choice of the integration method and the number of different …
Integration of proteomics and metabolomics data of early and middle season Hass avocados under heat treatment
VG Uarrota, C Fuentealba, I Hernández… - Food Chemistry, 2019 - Elsevier
Ripening heterogeneity of Hass avocados results in inconsistent quality fruit delivered to the
triggered and ready to eat markets. This research aimed to understand the effect of a heat …
triggered and ready to eat markets. This research aimed to understand the effect of a heat …
[HTML][HTML] A computational framework for complex disease stratification from multiple large-scale datasets
Background Multilevel data integration is becoming a major area of research in systems
biology. Within this area, multi-'omics datasets on complex diseases are becoming more …
biology. Within this area, multi-'omics datasets on complex diseases are becoming more …