Methods based on single-molecule localization and photophysics have brought nanoscale
imaging with visible light into reach. This has enabled single-particle tracking applications …

The rapid advancement of single-molecule localization microscopy (SMLM) provides
chances for visualizing biological structures and tracking their functions with unprecedented …

Synaptic transmission is maintained by a delicate, sub-synaptic molecular architecture, and
even mild alterations in synapse structure drive functional changes during experience …

Scaffolding molecules at the postsynaptic membrane form the foundation of excitatory
synaptic transmission by establishing the architecture of the postsynaptic density (PSD), but …

Highly accurate sample drift correction is essential in super-resolution localization
microscopy to guarantee a high spatial resolution, especially when the technique is used to …

When excited with rotating linear polarized light, differently oriented fluorescent dyes emit
periodic signals peaking at different times. We show that measurement of the average …

T cells become activated when T-cell receptors (TCRs) recognize agonist peptides bound to
major histocompatibility complex molecules on antigen-presenting cells. T-cell activation …

We derive distributional limits for empirical transport distances between probability
measures supported on countable sets. Our approach is based on sensitivity analysis of …

Single molecule localization microscopy (SMLM), which can provide up to an order of
magnitude improvement in spatial resolution over conventional fluorescence microscopy …

Background Super-resolution microscopy techniques are often extremely susceptible to
sample drift due to their high spatial resolution and the long time needed for data …