[HTML][HTML] Keloids: a review of etiology, prevention, and treatment

U Betarbet, TW Blalock - The Journal of clinical and aesthetic …, 2020 - ncbi.nlm.nih.gov
Keloids are abnormal scars that cause significant emotional and physical distress in patients
when inadequately treated. Keloid formation is theorized to occur as a result of an …

Current and upcoming therapies to modulate skin scarring and fibrosis

JQ Coentro, E Pugliese, G Hanley, M Raghunath… - Advanced drug delivery …, 2019 - Elsevier
Skin is the largest organ of the human body. Being the interface between the body and the
outer environment, makes it susceptible to physical injury. To maintain life, nature has …

Keloids and hypertrophic scars: pathophysiology, classification, and treatment

B Berman, A Maderal, B Raphael - Dermatologic Surgery, 2017 - journals.lww.com
BACKGROUND Keloid and hypertrophic scars represent an aberrant response to the wound
healing process. These scars are characterized by dysregulated growth with excessive …

[HTML][HTML] GEC-ESTRO ACROP recommendations in skin brachytherapy

JL Guinot, A Rembielak, J Perez-Calatayud… - Radiotherapy and …, 2018 - Elsevier
Purpose The aim of this publication is to compile available literature data and expert
experience regarding skin brachytherapy (BT) in order to produce general …

Keloids and hypertrophic scars

A Knowles, DA Glass - Dermatologic Clinics, 2023 - derm.theclinics.com
Keloids are an exaggerated fibroproliferative response to cutaneous wound healing in
which scar tissue grows excessively and invasively beyond the original wound borders …

[HTML][HTML] Integrated analysis of single-cell and spatial transcriptomics in keloids: highlights on fibrovascular interactions in keloid pathogenesis

J Shim, SJ Oh, E Yeo, JH Park, JH Bae, SH Kim… - Journal of Investigative …, 2022 - Elsevier
Studies on the etiopathogenesis of keloids mostly have focused on fibroblasts and their
dysfunction. In this study, two cutting-edge technologies, single-cell RNA sequencing and …

[HTML][HTML] Management of keloid scars: noninvasive and invasive treatments

SW Kim - Archives of plastic surgery, 2021 - thieme-connect.com
Scars vary from mature linear scars to abnormal excessive scars such as hypertrophic scars
and keloid scars. Keloid scars are fibro-proliferative disease entities that reflect an abnormal …

From genetics to epigenetics: new insights into keloid scarring

Y He, Z Deng, M Alghamdi, L Lu, MW Fear… - Cell proliferation, 2017 - Wiley Online Library
Keloid scarring is a dermal fibroproliferative response characterized by excessive and
progressive deposition of collagen; aetiology and molecular pathology underlying keloid …

Radiation therapy modalities for keloid management: a critical review

EK Liu, RF Cohen, ES Chiu - Journal of Plastic, Reconstructive & Aesthetic …, 2022 - Elsevier
Objective To provide a critical overview of current radiation modalities for keloid
management. Background Despite multimodal therapies, keloids that can develop following …

Radiation therapy in keloids treatment: history, strategy, effectiveness, and complication

J Xu, E Yang, NZ Yu, X Long - Chinese medical journal, 2017 - journals.lww.com
Objective: Radiation therapy combined with surgical excision was considered as one of the
most effective treatment plans for keloid lesions. However, there was no unanimity found …