Current status and applications of genome-scale metabolic models

C Gu, GB Kim, WJ Kim, HU Kim, SY Lee - Genome biology, 2019 - Springer
Genome-scale metabolic models (GEMs) computationally describe gene-protein-reaction
associations for entire metabolic genes in an organism, and can be simulated to predict …

Metabolomics and complementary techniques to investigate the plant phytochemical cosmos

H Tsugawa, A Rai, K Saito, R Nakabayashi - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to 2021 Plants and their associated microbial communities are known to
produce millions of metabolites, a majority of which are still not characterized and are …

Genome-wide prediction of metabolic enzymes, pathways, and gene clusters in plants

P Schläpfer, P Zhang, C Wang, T Kim, M Banf… - Plant …, 2017 - academic.oup.com
Plant metabolism underpins many traits of ecological and agronomic importance. Plants
produce numerous compounds to cope with their environments but the biosynthetic …

The ModelSEED Biochemistry Database for the integration of metabolic annotations and the reconstruction, comparison and analysis of metabolic models for plants …

SMD Seaver, F Liu, Q Zhang, J Jeffryes… - Nucleic acids …, 2021 - academic.oup.com
For over 10 years, ModelSEED has been a primary resource for the construction of draft
genome-scale metabolic models based on annotated microbial or plant genomes. Now …

Integrated omics analysis of specialized metabolism in medicinal plants

A Rai, K Saito, M Yamazaki - The Plant Journal, 2017 - Wiley Online Library
Medicinal plants are a rich source of highly diverse specialized metabolites with important
pharmacological properties. Until recently, plant biologists were limited in their ability to …

PATtyFams: protein families for the microbial genomes in the PATRIC database

JJ Davis, S Gerdes, GJ Olsen, R Olson… - Frontiers in …, 2016 - frontiersin.org
The ability to build accurate protein families is a fundamental operation in bioinformatics that
influences comparative analyses, genome annotation, and metabolic modeling. For several …

Remobilization of phytol from chlorophyll degradation is essential for tocopherol synthesis and growth of Arabidopsis

K Vom Dorp, G Hölzl, C Plohmann, M Eisenhut… - The Plant …, 2015 - academic.oup.com
Phytol from chlorophyll degradation can be phosphorylated to phytyl-phosphate and phytyl-
diphosphate, the substrate for tocopherol (vitamin E) synthesis. A candidate for the phytyl …

Updates in metabolomics tools and resources: 2014–2015

BB Misra, JJJ van der Hooft - Electrophoresis, 2016 - Wiley Online Library
Data processing and interpretation represent the most challenging and time‐consuming
steps in high‐throughput metabolomic experiments, regardless of the analytical platforms …

APAtrap: identification and quantification of alternative polyadenylation sites from RNA-seq data

C Ye, Y Long, G Ji, QQ Li, X Wu - Bioinformatics, 2018 - academic.oup.com
Motivation Alternative polyadenylation (APA) has been increasingly recognized as a crucial
mechanism that contributes to transcriptome diversity and gene expression regulation. As …

[HTML][HTML] Insights into the seed microbiome and its ecological significance in plant life

AF War, I Bashir, ZA Reshi, P Kardol, I Rashid - Microbiological Research, 2023 - Elsevier
In recent years, the microbiome has attracted much attention because of the multiple roles
and functions that microbes play in plants, animals, and human beings. Seed-associated …