Detergent-free isolation of membrane proteins and strategies to study them in a near-native membrane environment

B Krishnarjuna, A Ramamoorthy - Biomolecules, 2022 - mdpi.com
Atomic-resolution structural studies of membrane-associated proteins and peptides in a
membrane environment are important to fully understand their biological function and the …

Studying peptide-metal ion complex structures by solution-state NMR

DE Shalev - International Journal of Molecular Sciences, 2022 - mdpi.com
Metal chelation can provide structural stability and form reactive centers in metalloproteins.
Approximately one third of known protein structures are metalloproteins, and metal binding …

Characterization of nanodisc-forming peptides for membrane protein studies

B Krishnarjuna, G Sharma, SC Im, R Auchus… - Journal of Colloid and …, 2024 - Elsevier
Lipid-bilayer nanodiscs provide a stable, native-like membrane environment for the
functional and structural studies of membrane proteins and other membrane-binding …

Enhancing the stability and homogeneity of non-ionic polymer nanodiscs by tuning electrostatic interactions

B Krishnarjuna, J Marte, T Ravula… - Journal of colloid and …, 2023 - Elsevier
The nanodisc technology is increasingly used for structural studies on membrane proteins
and drug delivery. The development of synthetic polymer nanodiscs and the recent …

Sea anemone venom: Ecological interactions and bioactive potential

C Menezes, NL Thakur - Toxicon, 2022 - Elsevier
This article provides a brief overview of the literature related to the chemical ecology of sea
anemones, focusing on their venom, and summarizing their bioprospecting potential. Sea …

Never, Ever make an enemy… out of an anemone: Transcriptomic comparison of clownfish hosting sea anemone venoms

A Delgado, C Benedict, J Macrander, M Daly - Marine Drugs, 2022 - mdpi.com
Sea anemones are predatory marine invertebrates and have diverse venom arsenals.
Venom is integral to their biology, and is used in competition, defense, and feeding. Three …

Molecular Insights into the Low Complexity Secreted Venom of Calliactis polypus

HL Smith, DA Broszczak, SE Bryan… - Genome Biology and …, 2024 - academic.oup.com
Sea anemones are venomous animals that rely on their venom for prey capture, defense
against predators, and intraspecific competition. Currently, comprehensive molecular and …

[HTML][HTML] Structural and functional characterisation of Tst2, a novel TRPV1 inhibitory peptide from the Australian sea anemone Telmatactis stephensoni

KA Elnahriry, DCC Wai, LM Ashwood… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Sea anemone venoms are complex mixtures of biologically active compounds, including
disulfide-rich peptides, some of which have found applications as research tools, and others …

Recombinant production, NMR solution structure, and membrane interaction of the Phα1β toxin, a TRPA1 modulator from the Brazilian armed spider Phoneutria …

EN Lyukmanova, PA Mironov, DS Kulbatskii… - Toxins, 2023 - mdpi.com
Phα1β (PnTx3–6) is a neurotoxin from the spider Phoneutria nigriventer venom, originally
identified as an antagonist of two ion channels involved in nociception: N-type voltage-gated …

Diversity analysis of sea anemone peptide toxins in different tissues of Heteractis crispa based on transcriptomics

Q Guo, J Fu, L Yuan, Y Liao, M Li, X Li, B Yi, J Zhang… - Scientific Reports, 2024 - nature.com
Peptide toxins found in sea anemones venom have diverse properties that make them
important research subjects in the fields of pharmacology, neuroscience and biotechnology …