Understanding the role of sensorimotor beta oscillations

J Barone, HE Rossiter - Frontiers in Systems Neuroscience, 2021 - frontiersin.org
Beta oscillations have been predominantly observed in sensorimotor cortices and basal
ganglia structures and they are thought to be involved in somatosensory processing and …

Evolving concepts on bradykinesia

M Bologna, G Paparella, A Fasano, M Hallett… - Brain, 2020 - academic.oup.com
Bradykinesia is one of the cardinal motor symptoms of Parkinson's disease and other
parkinsonisms. The various clinical aspects related to bradykinesia and the …

Deep brain stimulation in movement disorders: from experimental surgery to evidence‐based therapy

P Krack, J Volkmann, G Tinkhauser… - Movement …, 2019 - Wiley Online Library
Deep brain stimulation (DBS) of 3 different targets is the most important therapeutic
innovation of the past 30 years for patients with fluctuating Parkinson's disease (PD) …

Human motor cortical beta bursts relate to movement planning and response errors

S Little, J Bonaiuto, G Barnes, S Bestmann - PLoS biology, 2019 - journals.plos.org
Motor cortical beta activity (13–30 Hz) is a hallmark signature of healthy and pathological
movement, but its behavioural relevance remains unclear. Using high-precision …

Driving motor cortex oscillations modulates bradykinesia in Parkinson's disease

A Guerra, D Colella, M Giangrosso, A Cannavacciuolo… - Brain, 2022 - academic.oup.com
In patients with Parkinson's disease, beta (β) and gamma (γ) oscillations are altered in the
basal ganglia, and this abnormality contributes to the pathophysiology of bradykinesia …

Biomarkers for closed-loop deep brain stimulation in Parkinson disease and beyond

W Bouthour, P Mégevand, J Donoghue… - Nature Reviews …, 2019 - nature.com
Subthalamic deep brain stimulation (DBS) for Parkinson disease (PD) currently requires
laborious open-loop programming, which can mitigate the benefits of this treatment …

[HTML][HTML] Local field potentials in Parkinson's disease: a frequency-based review

Z Yin, G Zhu, B Zhao, Y Bai, Y Jiang… - Neurobiology of …, 2021 - Elsevier
Deep brain stimulation (DBS) surgery offers a unique opportunity to record local field
potentials (LFPs), the electrophysiological population activity of neurons surrounding the …

The Pause-then-Cancel model of human action-stopping: Theoretical considerations and empirical evidence

DA Diesburg, JR Wessel - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
The ability to stop already-initiated actions is a key cognitive control ability. Recent work on
human action-stopping has been dominated by two controversial debates. First, the …

Debugging adaptive deep brain stimulation for Parkinson's disease

S Little, P Brown - Movement Disorders, 2020 - Wiley Online Library
Deep brain stimulation (DBS) is a successful treatment for patients with Parkinson's disease.
In adaptive DBS, stimulation is titrated according to feedback about clinical state and …

Subthalamic beta bursts correlate with dopamine-dependent motor symptoms in 106 Parkinson's patients

R Lofredi, L Okudzhava, F Irmen, C Brücke… - npj Parkinson's …, 2023 - nature.com
Pathologically increased beta power has been described as a biomarker for Parkinson's
disease (PD) and related to prolonged bursts of subthalamic beta synchronization. Here, we …