Pharmacological and biological effects of alpha-bisabolol: An updated review of the molecular mechanisms

E Ramazani, M Akaberi, SA Emami… - Life Sciences, 2022 - Elsevier
Abstract Alpha-bisabolol (α-bisabolol), an unsaturated monocyclic sesquiterpene alcohol, is
known as one of the “most-used herbal constituents” in the world. Various therapeutic and …

Health benefits, pharmacological effects, molecular mechanisms, and therapeutic potential of α-bisabolol

LB Eddin, NK Jha, SN Goyal, YO Agrawal… - Nutrients, 2022 - mdpi.com
α-Bisabolol is one of the important monocyclic sesquiterpenes, derived naturally from
essential oils of many edible and ornamental plants. It was first obtained from Matricaria …

Ethanolic Extract of Moringa oleifera Leaves Influences NF-κB Signaling Pathway to Restore Kidney Tissue from Cobalt-Mediated Oxidative Injury and Inflammation …

MM Abdel-Daim, SR Khalil, A Awad, EH Abu Zeid… - Nutrients, 2020 - mdpi.com
This study aimed to describe the protective efficacy of Moringa oleifera ethanolic extract
(MOEE) against the impact of cobalt chloride (CoCl2) exposure on the rat's kidney. Fifty male …

Targeting oxidative stress, a crucial challenge in renal transplantation outcome

R Carcy, M Cougnon, M Poet, M Durandy… - Free Radical Biology …, 2021 - Elsevier
Disorders characterized by ischemia/reperfusion (I/R) are the most common causes of
debilitating diseases and death in stroke, cardiovascular ischemia, acute kidney injury or …

Plants with therapeutic potential for ischemic acute kidney injury: A systematic review

A Ali, T Lima Sampaio, H Khan… - Evidence‐Based …, 2022 - Wiley Online Library
Acute kidney injury (AKI) is a complex condition which has an intricate pathology mostly
involving hemodynamic, inflammatory, and direct toxic effects at the cellular level with high …

[HTML][HTML] Eugenia uniflora (pitanga) leaf extract prevents the progression of experimental acute kidney injury

EF Meira, ND Oliveira, NP Mariani, ML Porto… - Journal of Functional …, 2020 - Elsevier
Acute kidney injury (AKI) is characterized by a rapid and potentially reversible decline in
renal function. We hypothesized that Eugenia uniflora (pitanga) may present a protective …

[HTML][HTML] New insights into the pathophysiological mechanisms underlying cardiorenal syndrome

J Wang, W Zhang, L Wu, Y Mei, S Cui, Z Feng… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Communication between the heart and kidney occurs through various bidirectional
pathways. The heart maintains continuous blood flow through the kidney while the kidney …

(−)-α-Bisabolol as a protective agent against epithelial renal cytotoxicity induced by amphotericin B

EP Magalhães, BP Silva, NL Aires, LR Ribeiro, A Ali… - Life Sciences, 2022 - Elsevier
Abstract Introduction Amphotericin B (AmB), used for systemic fungal infections, has a
limited clinical application because of its high nephrotoxicity. Natural antioxidant and anti …

Bioprospecting hydroxylated chalcones in in vitro model of ischemia-reoxygenation and probing NOX4 interactions via molecular docking

A Ali, IM de Almeida, EP Magalhães, JM Guedes… - Biological …, 2024 - degruyter.com
Ischemia/reperfusion injury (I/R) is a leading cause of acute kidney injury (AKI) in conditions
like kidney transplants, cardiac surgeries, and nephrectomy, contributing to high global …

[HTML][HTML] Therapeutic effects of the alkaline extract of leaves of Sasa sp. and elucidation of its mechanism in acute kidney injury

M Sano, Y Koseki, K Shibata, T Fujisawa… - Journal of …, 2024 - Elsevier
Acute kidney injury (AKI), a common complication in hospitalized patients, is associated with
high morbidity and mortality rates. However, there are currently no approved or effective …