A systematic review of the stability of extemporaneous pediatric oral formulations

A Belayneh, Z Tessema - The Scientific World Journal, 2021 - Wiley Online Library
Background. Extemporaneous compounding is a pharmacy practice to produce suitable
pharmaceutical preparations when there are no commercially available, licensed, and age …

[HTML][HTML] Exome Sequence Data of Eight SLC Transporters Reveal That SLC22A1 and SLC22A3 Variants Alter Metformin Pharmacokinetics and Glycemic Control

MI Morales-Rivera, R Alemón-Medina… - Pharmaceuticals, 2024 - mdpi.com
Background: Type 2 diabetes (T2D) is one of the leading causes of mortality and is a public
health challenge worldwide. Metformin is the first-choice treatment for T2D; its …

[PDF][PDF] Paediatric medicines: formulation considerations

F Roque - Arch Pharm Pharma Sci, 2017 - pharmacyscijournal.com
The use of unlicensed and off-label medicines in children is widespread and has raised an
increasing concern over the last years. The majority of medicines taken by children are …

[HTML][HTML] The L125F MATE1 variant enriched in populations of Amerindian origin is associated with increased plasma levels of metformin and lactate

MI Morales-Rivera, R Alemon-Medina… - Biomedicine & …, 2021 - Elsevier
Genetic factors that affect variability in metformin response have been poorly studied in the
Latin American population, despite its being the initial drug therapy for type 2 diabetes, one …

Comparative Bioavailability and Pharmacokinetics Between the Solid Form of Metformin vs a Novel Liquid Extemporaneous Formulation in Children

R Alemón-Medina… - Dose …, 2021 - journals.sagepub.com
Metformin pharmacokinetics in a liquid extemporaneous formulation from commercial tablets
was determined in paediatric patients. A randomized, transversal clinical trial was conducted …

Interacciones medicamento–nutriente y medicamento–planta medicinal en el tratamiento farmacológico de diabetes: revisión sistemática. Cuenca 2018

RDR Idrovo Muñoz, DM Ulloa Zeas - 2019 - dspace.ucuenca.edu.ec
Background. Type II diabetes mellitus is a chronic disease with a high prevalence worldwide
and metformin is the first line oral antidiabetic therapy for its treatment. The possible …

[PDF][PDF] Journal of Experimental and Clinical Application of Chinese Medicine

T Chen, X Zhang, W Zhang, Y Liu - Journal of Experimental and …, 2024 - exploverpub.com
The complex syndrome of obesity is a complex syndrome associated with various metabolic
disorders, poses significant threats to human health. Many weight loss medications have the …

The Effect of Storage Time on the Levels of Phthalates in Extemporaneous Preparations in Ghana

AO Adu, I Ayensu, AA Brobbey, SO Bekoe, D Azanu… - 2024 - researchsquare.com
The safety and quality of pharmaceutical products can be affected by chemical contaminants
that migrate into them, depending on the type and composition of the packaging material …

[HTML][HTML] Exploring the Potential of Lotus Leaf and Its Bioactive Compounds for Anti-obesity Interventions

L Chen, X Zhang, W Zhang… - Journal of Experimental …, 2024 - ojs.exploverpub.com
The complex syndrome of obesity is a complex syndrome associated with various metabolic
disorders, poses significant threats to human health. Many weight loss medications have the …

[HTML][HTML] Farmacocinética comparada de metformina, en forma sólida y en formulación extemporánea líquida para pediatría, en voluntarios adultos sanos

L Rivera-Espinosa, G Pérez-Guillé… - Acta pediátrica de …, 2016 - scielo.org.mx
ANTECEDENTES: fraccionar o pulverizar tabletas de metformina para ajustar dosis
pediátricas dificulta su administración, genera inestabilidad del fármaco (oxidación …