In the 1970s, an unknown virus was suspected for documented cases of transfusion-
associated hepatitis, a phenomenon called non-A, non-B hepatitis. In 1989, the infectious …

More than two decades of intense research has provided a detailed understanding of
hepatitis C virus (HCV), which chronically infects 2% of the world's population. This effort has …

The discovery of hepatitis C virus (HCV) in 1989 permitted basic research to unravel critical
components of a complex life cycle for this important human pathogen. HCV is a highly …

Hepatitis C virus (HCV) infects an estimated 170 million persons worldwide and thus
represents a viral pandemic, one that is five times as widespread as infection with the …

An estimated 170 million persons worldwide are infected with hepatitis C virus (HCV), a
major cause of chronic liver disease. Despite increasing knowledge of genome structure …

Hepatitis C virus (HCV) infection causes chronic liver diseases and is a global public health
problem. Detailed analyses of HCV have been hampered by the lack of viral culture …

Hepatitis C virus, a major human pathogen, produces infectious virus particles with several
unique features, such as an ability to interact with serum lipoproteins, a dizzyingly …

More than 500 million people worldwide are persistently infected with the hepatitis B virus
(HBV) and/or hepatitis C virus (HCV) and are at risk of developing chronic liver disease …

The absence of a robust cell culture model of hepatitis C virus (HCV) infection has severely
limited analysis of the HCV life cycle and the development of effective antivirals and …

Hepatitis C virus (HCV) infection is a global health problem affecting an estimated 170
million individuals worldwide. We report the identification of multiple independent adaptive …