Phytochemicals in cancer treatment: From preclinical studies to clinical practice

AS Choudhari, PC Mandave, M Deshpande… - Frontiers in …, 2020 - frontiersin.org
Cancer is a severe health problem that continues to be a leading cause of death worldwide.
Increasing knowledge of the molecular mechanisms underlying cancer progression has led …

A comprehensive review on nutraceuticals: therapy support and formulation challenges

V Puri, M Nagpal, I Singh, M Singh, GA Dhingra… - Nutrients, 2022 - mdpi.com
Nutraceuticals are the nourishing components (hybrid of nutrition and pharmaceuticals) that
are biologically active and possess capability for maintaining optimal health and benefits …

Molecular mechanisms of action of genistein in cancer: Recent advances

HS Tuli, MJ Tuorkey, F Thakral, K Sak… - Frontiers in …, 2019 - frontiersin.org
Background: Genistein is one among the several other known isoflavones that is found in
different soybeans and soy products. The chemical name of genistein is 4′, 5, 7 …

The hallmarks of flavonoids in cancer

LGS Ponte, ICB Pavan, MCS Mancini, LGS da Silva… - Molecules, 2021 - mdpi.com
Flavonoids represent an important group of bioactive compounds derived from plant-based
foods and beverages with known biological activity in cells. From the modulation of …

Genistein: a potent anti-breast cancer agent

SS Bhat, SK Prasad, C Shivamallu, KS Prasad… - Current Issues in …, 2021 - mdpi.com
Genistein is an isoflavonoid present in high quantities in soybeans. Possessing a wide
range of bioactives, it is being studied extensively for its tumoricidal effects. Investigations …

Current perspectives of the applications of polyphenols and flavonoids in cancer therapy

X Montané, O Kowalczyk, B Reig-Vano, A Bajek… - Molecules, 2020 - mdpi.com
The development of anticancer therapies that involve natural drugs has undergone
exponential growth in recent years. Among the natural compounds that produce beneficial …

Combination anticancer therapies using selected phytochemicals

WH Talib, D Awajan, RA Hamed, AO Azzam… - Molecules, 2022 - mdpi.com
Cancer is still one of the most widespread diseases globally, it is considered a vital health
challenge worldwide and one of the main barriers to long life expectancy. Due to the …

Dual role of endoplasmic reticulum stress-mediated unfolded protein response signaling pathway in carcinogenesis

N Siwecka, W Rozpędek, D Pytel… - International journal of …, 2019 - mdpi.com
Cancer constitutes a grave problem nowadays in view of the fact that it has become one of
the main causes of death worldwide. Poor clinical prognosis is presumably due to cancer …

The involvement of natural polyphenols in molecular mechanisms inducing apoptosis in tumor cells: A promising adjuvant in cancer therapy

A Chimento, A De Luca, M D'Amico… - International Journal of …, 2023 - mdpi.com
Various literature data show how a diet rich in vegetables could reduce the incidence of
several cancers due to the contribution of the natural polyphenols contained in them …

[HTML][HTML] Unraveling the therapeutic potential of natural products in the prevention and treatment of leukemia

H Goel, R Kumar, P Tanwar, TK Upadhyay… - Biomedicine & …, 2023 - Elsevier
Leukemia is a heterogeneous group of hematological malignancies distinguished by
differentiation blockage and uncontrolled proliferation of myeloid or lymphoid progenitor …