Neutrophils in inflammatory diseases: Unraveling the impact of their derived molecules and heterogeneity

B Riaz, S Sohn - Cells, 2023 - mdpi.com
Inflammatory diseases involve numerous disorders and medical conditions defined by an
insufficient level of self-tolerance. These diseases evolve over the course of a multi-step …

An updated review on abnormal epigenetic modifications in the pathogenesis of systemic lupus erythematosus

X Zhou, S Zhou, Y Li - Frontiers in Immunology, 2025 - frontiersin.org
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease. The inconsistent
prevalence of SLE between monozygotic twins suggests that environmental factors affect the …

Identification of SLC22A17 DNA methylation hotspot as a potential biomarker in cutaneous melanoma

A Lavoro, L Falzone, G Gattuso, GN Conti… - Journal of Translational …, 2024 - Springer
Background Cancer onset and progression are driven by genetic and epigenetic alterations
leading to oncogene activation and the silencing of tumor suppressor genes. Among …

Significant heightened methylation levels of RUNX3 gene promoter in patients with systemic lupus erythematosus

N Ehtesham, S Alesaeidi, D Mohammad Zadeh… - Lupus, 2024 - journals.sagepub.com
Objective Researchers are actively investigating new diagnostic and prognostic biomarkers
that offer improved sensitivity and specificity for systemic lupus erythematosus (SLE). One …

Recognition of differently expressed genes and DNA methylation markers in patients with Lupus nephritis

Z Liu, F Liu, J Xie, Z Zhao, S Pan, D Liu… - Journal of Translational …, 2024 - degruyter.com
Abstract Background and Objectives Systemic lupus erythematosus (SLE) is distinguished
by dysregulated immune system activity, resulting in a spectrum of clinical manifestations …

Methyl-donor supplementation in women with systemic lupus erythematosus with different nutritional status: the protocol for a randomised, double-blind, placebo …

JCNL da Mota, LM Carvalho, AA Ribeiro… - Lupus Science & …, 2024 - lupus.bmj.com
Introduction DNA hypomethylation in patients with systemic lupus erythematosus (SLE) has
been recently documented in the literature. Low levels of DNA methylation have been …

Epigenetic biomarkers in personalized medicine

A Stoccoro, F Coppedè, L Migliore - Personalized Epigenetics, 2024 - Elsevier
Increasing evidence reveals that epigenetic biomarkers, mainly markers of DNA methylation
or noncoding RNA molecules, can become valuable tools as minimally invasive diagnostic …

MMP9 gene expression alterations in gastric cancer and their role in cell migration

A Farhadi, ZK Shohre, E Mehdi - Medical Journal of Tabriz …, 2024 - mj.tbzmed.ac.ir
Background. Gastric cancer (GC) is a significant global health concern, ranking as the fifth
most common malignant tumor and the fourth leading cause of cancer-related deaths …