The study of innate immunity and its link to inflammation and host defense encompasses
diverse areas of biology, ranging from genetics and biophysics to signal transduction and …

Simple Summary Microbial resistance to antibiotics is a constant threat to livestock farming,
and unreasonable use of antibiotics has increased the prevalence of infectious diseases in …

The identification of the Drosophila melanogaster Toll pathway cascade and the subsequent
characterization of TLRs have reshaped our understanding of the immune system. Ever …

In an environment rich in potentially harmful microbes, plant survival depends on efficient
microbe perception and fast defense responses. Contrary to the mammalian immune system …

The NF-κB pathway is a ubiquitous stress response that activates the NF-κB family of
transcription factors. Antigen receptors, receptors of the innate immune system, and certain …

Kawasaki disease (KD) is a medium vessel vasculitis that affects young children. Despite
extensive research over the last 50 years, the etiology of KD remains an enigma. Seasonal …

Thymoquinone (TQ) is a bioactive component of black seed (Nigella sativa) volatile oil and
has been shown to have anti-oxidative, anti-inflammatory, and anti-cancer properties. In the …

Toll-like receptors (TLRs) play critical roles in host defense against microbes. In the past
decade, growing numbers of in vitro, in vivo and in silico studies have been performed and …

Plasmacytoid dendritic cells (pDCs), also known as type I interferon (IFN)-producing cells,
are specialized immune cells characterized by their extraordinary capabilities of mounting …

Specific microRNA (miRNA) signatures have been associated with different cytogenetic
subtypes in acute leukemias. This finding prompted us to investigate potential associations …