An overview of the immunological defenses in fish skin

M Ángeles Esteban - International scholarly research notices, 2012 - Wiley Online Library
The vertebrate immune system is comprised of numerous distinct and interdependent
components. Every component has its own inherent protective value, and the final …

Current scenario of peptide-based drugs: the key roles of cationic antitumor and antiviral peptides

KCL Mulder, LA Lima, VJ Miranda, SC Dias… - Frontiers in …, 2013 - frontiersin.org
Cationic antimicrobial peptides (AMPs) and host defense peptides (HDPs) show vast
potential as peptide-based drugs. Great effort has been made in order to exploit their …

Applications of antimicrobial peptides from fish and perspectives for the future

V Rajanbabu, JY Chen - Peptides, 2011 - Elsevier
Fish are a major component of the aquatic fauna. Like other organisms, fish secrete different
kinds of antimicrobial peptides (AMPs), which are positively charged short amino-acid-chain …

On the selectivity and efficacy of defense peptides with respect to cancer cells

F Harris, SR Dennison, J Singh… - Medicinal research …, 2013 - Wiley Online Library
Here, we review potential determinants of the anticancer efficacy of innate immune peptides
(ACPs) for cancer cells. These determinants include membrane‐based factors, such as …

Road to clinical efficacy: challenges and novel strategies for antimicrobial peptide development

R Eckert - Future microbiology, 2011 - Taylor & Francis
Since the discovery of magainins, cecropins and defensins 30 years ago, antimicrobial
peptides (AMPs) have been hailed as a potential solution to the dearth of novel antibiotic …

Antimicrobial peptides and other peptide-like therapeutics as promising candidates to combat SARS-CoV-2

MS Mousavi Maleki, M Rostamian… - Expert review of anti …, 2021 - Taylor & Francis
Introduction: There are currently no specific drugs and universal vaccines for Coronavirus
disease 2019 (COVID-19), hence urgent effective measures are needed to discover and …

Fish mucosal immunity: skin

MÁ Esteban, R Cerezuela - Mucosal health in aquaculture, 2015 - Elsevier
In this chapter, the current knowledge of mucosal immunity in fish skin is described. Skin is
considered the largest immunologically active organ in fish and is remarkably different from …

Fish skin mucus extracts: an underexplored source of antimicrobial agents

R Díaz-Puertas, M Adamek, R Mallavia, A Falco - Marine Drugs, 2023 - mdpi.com
The slow discovery of new antibiotics combined with the alarming emergence of antibiotic-
resistant bacteria underscores the need for alternative treatments. In this regard, fish skin …

Innate immune responses of salmonid fish to viral infections

B Collet - Developmental & Comparative Immunology, 2014 - Elsevier
Viruses are the most serious pathogenic threat to the production of the main aquacultured
salmonid species the rainbow trout Oncorhynchus mykiss and the Atlantic salmon Salmo …

Effect of helical kink in antimicrobial peptides on membrane pore formation

A Tuerkova, I Kabelka, T Králová, L Sukeník, Š Pokorná… - Elife, 2020 - elifesciences.org
Every cell is protected by a semipermeable membrane. Peptides with the right properties, for
example Antimicrobial peptides (AMPs), can disrupt this protective barrier by formation of …