The authors performed a meta-analysis to estimate the magnitude of polymorphism effects
for the complement component C3 gene (C3) and their possible mode of action on age …

Age-related macular degeneration (AMD) is a progressive degenerative disease which
leads to blindness, affecting the quality of life of millions of Americans. More than 1.75 …

Purpose.: We explored associations between age-related macular degeneration (AMD) and
genetic variants of 10 genes in a nationwide Chinese population. Methods.: In this …

The authors performed a systematic review of the association of complement component 2
(C2)/complement factor B (CFB) gene polymorphisms with age-related macular …

Age-related macular degeneration (AMD) is a major late-onset posterior eye disease that
causes central vision to deteriorate among elderly populations. The predominant lesion of …

Background: Several previous studies have assessed the contribution of polymorphisms in
genes encoding the complement factors C2/C3/CFB/CFH with the risk of age-related …

Aims: To determine whether there is an association between CFH, ARMS2, HTRA1, VEGF,
SERPING1 or C3 genotypes and patient response to treatment with intravitreal bevacizumab …

Purpose.: It has been hypothesized that the macular carotenoids protect against age-related
macular degeneration (AMD). In this study, the association between serum concentrations of …

Background: With the increasing number of studies indicating that two single-nucleotide
polymorphisms (SNPs), rs1061170 and rs1410996, in complement factor H (CFH) might be …

Background The purpose of this study is to discuss whether genetic variants (rs2230199,
rs1047286, rs2230205, and rs2250656) in the C3 gene account for a significant risk of …