The colorectal cancer tumor microenvironment and its impact on liver and lung metastasis
Simple Summary Colorectal cancer (CRC) is the third most common cancer worldwide.
Metastasis to secondary organs, such as the liver and lungs, is a key driver of CRC-related …
Metastasis to secondary organs, such as the liver and lungs, is a key driver of CRC-related …
The oligometastatic spectrum in the era of improved detection and modern systemic therapy
Metastases remain the leading cause of cancer-related mortality. The oligometastasis
hypothesis postulates that a spectrum of metastatic spread exists and that some patients …
hypothesis postulates that a spectrum of metastatic spread exists and that some patients …
Stereotactic ablative radiotherapy for the comprehensive treatment of oligometastatic cancers: long-term results of the SABR-COMET phase II randomized trial
PURPOSE The oligometastatic paradigm hypothesizes that patients with a limited number of
metastases may achieve long-term disease control, or even cure, if all sites of disease can …
metastases may achieve long-term disease control, or even cure, if all sites of disease can …
Pulmonary metastasectomy in colorectal cancer: updated analysis of 93 randomized patients–control survival is much better than previously assumed
M Milosevic, J Edwards, D Tsang, J Dunning… - Colorectal …, 2020 - Wiley Online Library
Aim Lung metastases from colorectal cancer are resected in selected patients in the belief
that this confers a significant survival advantage. It is generally assumed that the 5‐year …
that this confers a significant survival advantage. It is generally assumed that the 5‐year …
Single-fraction vs multifraction stereotactic ablative body radiotherapy for pulmonary oligometastases (SAFRON II): the trans tasman radiation oncology group 13.01 …
Importance Evidence is lacking from randomized clinical trials to guide the optimal approach
for stereotactic ablative body radiotherapy (SABR) in patients with pulmonary …
for stereotactic ablative body radiotherapy (SABR) in patients with pulmonary …
Repeated centralized multidisciplinary team assessment of resectability, clinical behavior, and outcomes in 1086 Finnish metastatic colorectal cancer patients (RAXO) …
P Osterlund, T Salminen, LM Soveri… - The Lancet Regional …, 2021 - thelancet.com
Background Resection of colorectal cancer (CRC) metastases provides good survival but is
probably underused in real-world practice. Methods A prospective Finnish nationwide study …
probably underused in real-world practice. Methods A prospective Finnish nationwide study …
The Pulmonary Metastasectomy in Colorectal Cancer cohort study: Analysis of case selection, risk factors and survival in a prospective observational study of 512 …
T Treasure, V Farewell, F Macbeth… - Colorectal …, 2021 - Wiley Online Library
Aim We wanted to examine survival in patients with resected colorectal cancer (CRC) whose
lung metastases are or are not resected. Methods Teams participating in the study of …
lung metastases are or are not resected. Methods Teams participating in the study of …
Oligometastases: emerging evidence
The hypothesis that ablative therapies (such as surgery or radiation) can be used to cure
patients with a limited number of metastases was influential in changing practice. Early …
patients with a limited number of metastases was influential in changing practice. Early …
[HTML][HTML] The extracellular matrix in colorectal cancer and its metastatic settling–Alterations and biological implications
S Karlsson, H Nyström - Critical reviews in oncology/hematology, 2022 - Elsevier
Colorectal cancer (CRC) remains one of the most common cancers worldwide. Metastatic
disease is ultimately fatal when incurable. Cancer research has evolved to take the …
disease is ultimately fatal when incurable. Cancer research has evolved to take the …
[HTML][HTML] Management of single pulmonary metastases from colorectal cancer: State of the art
Colorectal cancer (CRC) is one of the most common causes of death from cancer. Lung
seeding occurs in approximately 10% of patients surgically treated for primary CRC with …
seeding occurs in approximately 10% of patients surgically treated for primary CRC with …