Modulating microbiota as a new strategy for breast cancer prevention and treatment

H Wu, S Ganguly, TO Tollefsbol - Microorganisms, 2022 - mdpi.com
Breast cancer (BC) is the most common cancer in women in the United States. There has
been an increasing incidence and decreasing mortality rate of BC cases over the past …

Microbiomes, their function, and cancer: how metatranscriptomics can close the knowledge gap

L Aitmanaitė, K Širmonaitis, G Russo - International journal of molecular …, 2023 - mdpi.com
The interaction between the microbial communities in the human body and the onset and
progression of cancer has not been investigated until recently. The vast majority of the …

Exploring breast tissue microbial composition and the association with breast cancer risk factors

R German, N Marino, C Hemmerich, R Podicheti… - Breast Cancer …, 2023 - Springer
Background Microbial dysbiosis has emerged as an important element in the development
and progression of various cancers, including breast cancer. However, the microbial …

In-silico characterization of estrogen reactivating β-glucuronidase enzyme in git associated microbiota of normal human and breast cancer patients

F Muccee, S Ghazanfar, W Ajmal, M Al-Zahrani - Genes, 2022 - mdpi.com
Estrogen circulating in blood has been proved to be a strong biomarker for breast cancer. A
β-glucuronidase enzyme (GUS) from human gastrointestinal tract (GIT) microbiota including …

Role of the intratumoral microbiome in tumor progression and therapeutics implications

YF Meng, ZY Fan, B Zhou, HX Zhan - … et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
Microbes are widely present in various organs of the human body and play important roles
in numerous physiological and pathological processes. Nevertheless, owing to multiple …

Mendelian randomization analysis revealed a gut microbiota–mammary axis in breast cancer

S Zhang, W Zhang, H Ren, R Xue, Z Wang… - Frontiers in …, 2023 - frontiersin.org
Background Observational epidemiological studies suggested an association between the
gut microbiota and breast cancer, but it remains unclear whether the gut microbiota causally …

Guideline for designing microbiome studies in neoplastic diseases

E Mikó, A Sipos, E Tóth, A Lehoczki, M Fekete, É Sebő… - Geroscience, 2024 - Springer
Oncobiosis has emerged as a key contributor to the development, and modulator of the
treatment efficacy of cancer. Hereby, we review the modalities through which the oncobiome …

[HTML][HTML] The role of transcription factors in the acquisition of the four latest proposed hallmarks of cancer and corresponding enabling characteristics

MP Morgan, E Finnegan, S Das - Seminars in cancer biology, 2022 - Elsevier
With the recent description of the molecular and cellular characteristics that enable
acquisition of both core and new hallmarks of cancer, the consequences of transcription …

The link between the microbiota and HER2+ breast cancer: the new challenge of precision medicine

M Di Modica, V Arlotta, L Sfondrini, E Tagliabue… - Frontiers in …, 2022 - frontiersin.org
The microbiota is emerging as a key player in cancer due to its involvement in several host
physiological functions, including digestion, development of the immune system, and …

Impact of intestinal dysbiosis on breast cancer metastasis and progression

J Zhang, Q Xie, X Huo, Z Liu, M Da, M Yuan… - Frontiers in …, 2022 - frontiersin.org
Breast cancer has a high mortality rate among malignant tumors, with metastases identified
as the main cause of the high mortality. Dysbiosis of the gut microbiota has become a key …