The tumor microenvironment is highly complex, and immune escape is currently considered
an important hallmark of cancer, largely contributing to tumor progression and metastasis …

Rho GTPases are a family of small G proteins that regulate a wide array of cellular
processes related to their key roles controlling the cytoskeleton. Cancer is a multistep …

Simple Summary The epithelial to mesenchymal transition (EMT) is a well-documented
process in the study of cancer metastases. The cytoskeleton is an intricate network involved …

Recent years have seen a renaissance in the research linking inflammation and cancer with
immune cells playing a central role in smouldering inflammation in the tumor …

Increased levels of total tumor-infiltrating lymphocytes (TILs) are generally associated with
good prognosis in several breast cancer subtypes. Subtypes of TILs impact both tumor cells …

Breast cancer (BC) is the main cause of cancer-related mortality among women globally.
Despite substantial advances in the identification and management of primary tumors …

Cell–cell interfaces are found throughout multicellular organisms, from transient interactions
between motile immune cells to long-lived cell–cell contacts in epithelia. Studies of immune …

Cytotoxic lymphocytes are critical in our immune defence against cancer and infection.
Cytotoxic T lymphocytes and Natural Killer cells can directly lyse malignant or infected cells …

Natural killer (NK) cells are major contributors to immunosurveillance and control of tumor
development by inducing apoptosis of malignant cells. Among the main mechanisms …

Natural killer (NK) cells are innate lymphoid cells, which play key roles in elimination of
virally infected and malignant cells. The balance between activating and inhibitory signals …