Piper betle (L): Recent Review of Antibacterial and Antifungal Properties, Safety Profiles, and Commercial Applications

NMDMW Nayaka, MMV Sasadara, DA Sanjaya… - Molecules, 2021 - mdpi.com
Piper betle (L) is a popular medicinal plant in Asia. Plant leaves have been used as a
traditional medicine to treat various health conditions. It is highly abundant and inexpensive …

Recent advances in antimicrobial nano-drug delivery systems

TX Zong, AP Silveira, JAV Morais, MC Sampaio… - Nanomaterials, 2022 - mdpi.com
Infectious diseases are among the major health issues of the 21st century. The substantial
use of antibiotics over the years has contributed to the dissemination of multidrug resistant …

Effects of Piper betle fractionated extracts on inhibition of Streptococcus mutans and Streptococcus intermedius

P Phumat, S Khongkhunthian… - Drug discoveries & …, 2018 - jstage.jst.go.jp
The overgrowth of certain strains of normal flora in oral cavity can cause many kinds of oral
infections or diseases such as carries, periodontitis, and gingivitis. Prevention and treatment …

Comparative inhibitory effects of 4-allylpyrocatechol isolated from Piper betle on Streptococcus intermedius, Streptococcus mutans, and Candida albicans

P Phumat, S Khongkhunthian, P Wanachantararak… - Archives of oral …, 2020 - Elsevier
Streptococcus intermedius, Streptococcus mutans, and Candida albicans are harmful oral
pathogens and prone to resist chemical antimicrobial agents. Active ingredients from plants …

Development of Self-Nanoemulsifying Drug Delivery Systems Containing 4-Allylpyrocatechol for Treatment of Oral Infections Caused by Candida albicans

S Okonogi, P Phumat, S Khongkhunthian… - Pharmaceutics, 2021 - mdpi.com
Clinical use of 4-Allylpyrocatechol (APC), a potential antifungal agent from Piper betle, is
limited because of its low water solubility. The current study explores the development of the …

[HTML][HTML] Anticariogenic potential of Korean native plant extracts against Streptococcus mutans

YC Lee, SG Cho, SW Kim, JN Kim - Planta medica, 2019 - thieme-connect.com
Numerous chemically synthesized compounds are widely used in oral hygiene products.
However, due to their potential risk, there is a need to improve the safety and quality of …

Denture-Soaking Solution Containing Piper betle Extract-Loaded Polymeric Micelles; Inhibition of Candida albicans, Clinical Study, and Effects on Denture Base …

S Okonogi, P Phumat, S Khongkhunthian, K Suttiat… - Antibiotics, 2021 - mdpi.com
Candida albicans is a common overgrowth in people wearing dentures. Long-term use of
antifungal chemicals carries a risk of toxic side effects. This study focused on the edible …

[HTML][HTML] A Scoping Review on Medicinal Properties of Piper betle (Sirih) Based on Malay Medical Manuscripts and Scientific Literatures

NFI Zamri, MAM Shafri, Z Zamli… - The Malaysian journal of …, 2023 - ncbi.nlm.nih.gov
Background Malay medical manuscripts have deciphered the medicinal value of Piper betle
(sirih) enormously. In this review, an effort was made to explore the medicinal use of P. betle …

Characterization and analysis of the bioactivity of the Piper rivinoides Kunth essential oil and its components myristicin and elemicin, against opportunistic fungal …

VJA Fonseca, SC Dos Santos, JNP Carneiro… - Microbial …, 2025 - Elsevier
Candidiasis is an infectious disease caused by some fungi of the genus Candida. In Brazil,
the incidence rate is higher than in European countries and the United States, and health …

Optimization of short-term dynamic and static maceration of Piper betle L. leaves to maximize extraction yield and anti-Candida albicans activity

N Lakkana, T Wunnakup, J Suksaeree… - Journal of Biologically …, 2024 - Taylor & Francis
This study aimed to optimize the extraction conditions of Piper betle leaves using a
circumscribed central composite design, comparing dynamic and static maceration …