Hepatitis C virus (HCV) is a hepatotropic RNA virus that causes progressive liver damage,
which might result in liver cirrhosis and hepatocellular carcinoma. Globally, between 64 and …

We are entering an important new chapter in the story of hepatitis C virus (HCV) infection.
There are clear challenges and opportunities. On the one hand, new HCV infections are still …

BACKGROUND & AIMS:: A sustained virologic response (SVR) to therapy for hepatitis C
virus (HCV) infection is defined as the inability to detect HCV RNA 24 weeks after …

Virally induced liver cancer usually evolves over long periods of time in the context of a
strongly oxidative microenvironment, characterized by chronic liver inflammation and …

Background The goal of chronic hepatitis C treatment is to remove the virus to avoid
progression of HCV-related disease. Sustained virologic response (SVR) is the most widely …

Chronic hepatitis C (CHC) is associated with multiple extrahepatic manifestations that may
impact infected patients. The mechanisms through which these develop include those which …

Background The burden of HCV cirrhosis is high and projected to increase significantly over
the next decade. While interferon therapy is problematic in HCV cirrhosis, the era of direct …

Background Treatment for chronic hepatitis C (CH‐C) is rapidly changing and moving away
from an interferon and ribavirin‐based therapy to interferon‐free ribavirin‐free all oral …

BACKGROUND: Liver biopsy is the reference standard for diagnosing the extent of fibrosis
in chronic liver disease; however, it is invasive, with the potential for serious complications …

Treatment with interferon (IFN) and ribavirin (RBV) significantly impairs quality of life and
other patient‐reported outcomes (PROs). Patient experience with IFN‐and RBV‐free anti …