Extracellular matrix-based biomaterial scaffolds and the host response
JM Aamodt, DW Grainger - Biomaterials, 2016 - Elsevier
Extracellular matrix (ECM) collectively represents a class of naturally derived proteinaceous
biomaterials purified from harvested organs and tissues with increasing scientific focus and …
biomaterials purified from harvested organs and tissues with increasing scientific focus and …
Collagen—emerging collagen based therapies hit the patient
The choice of biomaterials available for regenerative medicine continues to grow rapidly,
with new materials often claiming advantages over the short-comings of those already in …
with new materials often claiming advantages over the short-comings of those already in …
The impact of detergents on the tissue decellularization process: a ToF-SIMS study
Biologic scaffolds are derived from mammalian tissues, which must be decellularized to
remove cellular antigens that would otherwise incite an adverse immune response …
remove cellular antigens that would otherwise incite an adverse immune response …
Macrophage phenotype as a predictor of constructive remodeling following the implantation of biologically derived surgical mesh materials
Macrophages have been classified as having plastic phenotypes which exist along a
spectrum between M1 (classically activated; pro-inflammatory) and M2 (alternatively …
spectrum between M1 (classically activated; pro-inflammatory) and M2 (alternatively …
Consequences of ineffective decellularization of biologic scaffolds on the host response
Biologic scaffold materials composed of extracellular matrix (ECM) are routinely used for a
variety of clinical applications. Despite known variations in tissue remodeling outcomes …
variety of clinical applications. Despite known variations in tissue remodeling outcomes …
Extracellular matrix-based biomaterials and their influence upon cell behavior
MC Cramer, SF Badylak - Annals of biomedical engineering, 2020 - Springer
Biologic scaffold materials composed of allogeneic or xenogeneic extracellular matrix (ECM)
are commonly used for the repair and remodeling of injured tissue. The clinical outcomes …
are commonly used for the repair and remodeling of injured tissue. The clinical outcomes …
The effects of processing methods upon mechanical and biologic properties of porcine dermal extracellular matrix scaffolds
Biologic materials from various species and tissues are commonly used as surgical meshes
or scaffolds for tissue reconstruction. Extracellular matrix (ECM) represents the secreted …
or scaffolds for tissue reconstruction. Extracellular matrix (ECM) represents the secreted …
Perfusion-decellularized pancreas as a natural 3D scaffold for pancreatic tissue and whole organ engineering
Approximately 285 million people worldwide suffer from diabetes, with insulin
supplementation as the most common treatment measure. Regenerative medicine …
supplementation as the most common treatment measure. Regenerative medicine …
The promotion of a constructive macrophage phenotype by solubilized extracellular matrix
BM Sicari, JL Dziki, BF Siu, CJ Medberry, CL Dearth… - Biomaterials, 2014 - Elsevier
The regenerative healing response of injured skeletal muscle is dependent upon a
heterogeneous population of responding macrophages, which show a phenotypic transition …
heterogeneous population of responding macrophages, which show a phenotypic transition …
Collagen: a network for regenerative medicine
KM Pawelec, SM Best, RE Cameron - Journal of Materials Chemistry B, 2016 - pubs.rsc.org
The basic building block of the extra-cellular matrix in native tissue is collagen. As a
structural protein, collagen has an inherent biocompatibility making it an ideal material for …
structural protein, collagen has an inherent biocompatibility making it an ideal material for …