Cortical networks are composed of glutamatergic excitatory projection neurons and local
GABAergic inhibitory interneurons that gate signal flow and sculpt network dynamics …

One of the most captivating questions in neuroscience revolves around the brain's ability to
efficiently and durably capture and store information. It must process continuous input from …

The human cerebral cortex houses 1000 times more neurons than that of the cerebral cortex
of a mouse, but the possible differences in synaptic circuits between these species are still …

Neurons are frequently classified into distinct types on the basis of structural, physiological,
or genetic attributes. To better constrain the definition of neuronal cell types, we …

In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

Cortical inhibitory neurons contact each other to form a network of inhibitory synaptic
connections. Our knowledge of the connectivity pattern underlying this inhibitory network is …

An understanding of the diversity of cortical GABAergic interneurons is critical to understand
the function of the cerebral cortex. Recent data suggest that neurons expressing three …

INTRODUCTION The intricate microcircuitry of the cerebral cortex is thought to be a critical
substrate from which arise the impressive capabilities of the mammalian brain. Until now …

Mammals adapt to a rapidly changing world because of the sophisticated cognitive functions
that are supported by the neocortex. The neocortex, which forms almost 80% of the human …

A highly diverse population of neocortical GABAergic inhibitory interneurons has been
implicated in multiple functions in information processing within cortical circuits. The diversity …