Normothermic machine perfusion (NMP) aims to preserve organs ex vivo by simulating
physiological conditions such as body temperature. Recent advancements in NMP system …

Extracellular vesicles (EVs) are emerging as a promising field of research in liver disease.
EVs are small, membrane-bound vesicles that contain various bioactive molecules, such as …

Extracellular vesicles are lipid bilayer-delimited nanoparticles excreted into the extracellular
space by all cells. They carry a cargo rich in proteins, lipids and DNA, as well as a full …

Liver allograft steatosis is a significant risk factor for postoperative graft dysfunction and has
been associated with inferior patient and graft survival, particularly in the case of moderate …

Organ transplantation is essential and crucial for saving and enhancing the lives of
individuals suffering from end-stage organ failure. Major challenges in the medical field …

Background The possible beneficial effects of stem cell-derived EV on ischemia-reperfusion
injury (IRI) in organ transplantation have been frequently investigated; however, the source …

End-stage liver disease patients undergoing liver transplantation are prone to develop
numerous infectious complications because of immunosuppression, surgical interventions …

Liver transplantation is the most effective treatment for end-stage liver disease. Transplant
indications have been progressively increasing, with a huge discrepancy between the …

The use of extended criteria donor grafts is a promising strategy to increase the number of
organ transplantations and reduce waitlist mortality. However, these organs are often …

Organ preservation and assessment with machine perfusion (MP) has provided transplant
physicians with the ability to evaluate and select grafts suitable for transplantation …