Is there a maternal blood biomarker that can predict spontaneous preterm birth prior to labour onset? A systematic review
KK Hornaday, EM Wood, DM Slater - PloS one, 2022 - journals.plos.org
Introduction The ability to predict spontaneous preterm birth (sPTB) prior to labour onset is a
challenge, and it is currently unclear which biomarker (s), may be potentially predictive of …
challenge, and it is currently unclear which biomarker (s), may be potentially predictive of …
Omics approaches: interactions at the maternal–fetal interface and origins of child health and disease
Immunoperinatology is an emerging field. Transdisciplinary efforts by physicians, physician‐
scientists, basic science researchers, and computational biologists have made substantial …
scientists, basic science researchers, and computational biologists have made substantial …
[HTML][HTML] A single-cell atlas of the myometrium in human parturition
Parturition is a well-orchestrated process characterized by increased uterine contractility,
cervical ripening, and activation of the chorioamniotic membranes; yet, the transition from a …
cervical ripening, and activation of the chorioamniotic membranes; yet, the transition from a …
Multiomic signals associated with maternal epidemiological factors contributing to preterm birth in low-and middle-income countries
Preterm birth (PTB) is the leading cause of death in children under five, yet comprehensive
studies are hindered by its multiple complex etiologies. Epidemiological associations …
studies are hindered by its multiple complex etiologies. Epidemiological associations …
[HTML][HTML] Microbiome preterm birth DREAM challenge: crowdsourcing machine learning approaches to advance preterm birth research
Every year, 11% of infants are born preterm with significant health consequences, with the
vaginal microbiome a risk factor for preterm birth. We crowdsource models to predict (1) …
vaginal microbiome a risk factor for preterm birth. We crowdsource models to predict (1) …
Deciphering maternal-fetal cross-talk in the human placenta during parturition using single-cell RNA sequencing
Labor is a complex physiological process requiring a well-orchestrated dialogue between
the mother and fetus. However, the cellular contributions and communications that facilitate …
the mother and fetus. However, the cellular contributions and communications that facilitate …
Human plasma proteome during normal pregnancy
The human plasma proteome is underexplored despite its potential value for monitoring
health and disease. Herein, using a recently developed aptamer-based platform, we profiled …
health and disease. Herein, using a recently developed aptamer-based platform, we profiled …
The vaginal immunoproteome for the prediction of spontaneous preterm birth: A retrospective longitudinal study
Background: Preterm birth is the leading cause of neonatal morbidity and mortality
worldwide. Most cases of preterm birth occur spontaneously and result from preterm labor …
worldwide. Most cases of preterm birth occur spontaneously and result from preterm labor …
The role of genetics in preterm birth
EC Mead, CA Wang, J Phung, JYX Fu… - Reproductive …, 2023 - Springer
Preterm birth (PTB), defined as the birth of a child before 37 completed weeks gestation,
affects approximately 11% of live births and is the leading cause of death in children under 5 …
affects approximately 11% of live births and is the leading cause of death in children under 5 …
Maternal factors during pregnancy influencing maternal, fetal, and childhood outcomes
Enhancing pregnancy health is known to improve the mother's and offspring's life-long well-
being. The maternal environment, encompassing genetic factors, impacts of social …
being. The maternal environment, encompassing genetic factors, impacts of social …