Retinal imaging biomarkers of Alzheimer's disease: A systematic review and meta‐analysis of studies using brain amyloid beta status for case definition

G Ashraf, M McGuinness, MA Khan… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction We performed a systematic review and meta‐analysis of the association
between retinal imaging parameters and Alzheimer's disease (AD). Methods PubMed …

Association between retinal markers and cognition in older adults: a systematic review

V Jeevakumar, R Sefton, J Chan, B Gopinath, G Liew… - BMJ open, 2022 - bmjopen.bmj.com
Objectives To appraise the existing literature reporting an association between retinal
markers and cognitive impairment in adults aged 65 years and over and to provide …

Feasibility study for detection of retinal amyloid in clinical trials: the Anti‐Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) trial

J Ngolab, M Donohue, A Belsha… - Alzheimer's & …, 2021 - Wiley Online Library
Introduction The retina and brain exhibit similar pathologies in patients diagnosed with
neurodegenerative diseases. The ability to access the retina through imaging techniques …

Associations between thinner retinal neuronal layers and suboptimal brain structural integrity in a middle-aged cohort

A Barrett-Young, WC Abraham, CY Cheung, J Gale… - Eye and …, 2023 - Taylor & Francis
Purpose The retina has potential as a biomarker of brain health and Alzheimer's disease
(AD) because it is the only part of the central nervous system which can be easily imaged …

Inhalable thioflavin S for the detection of amyloid beta deposits in the retina

SM Barton, E To, BP Rogers, C Whitmore, M Uppal… - Molecules, 2021 - mdpi.com
We present an integrated delivery technology herein employing the aerosolized method to
repurpose thioflavin S for imaging amyloid beta (Abeta) deposits in the retina as a surrogate …

Multiscale Analysis of Alzheimer's Disease Using Feature Fusion in Cognitive and Sensory Brain Regions

A Hassouneh, A Danna-dos-Santos, B Bazuin… - Digital …, 2024 - karger.com
Introduction: This research is focused on early detection of Alzheimer's disease (AD) using a
multiscale feature fusion framework, combining biomarkers from memory, vision, and …

Correlation between retinal structure and brain multimodal magnetic resonance imaging in patients with Alzheimer's disease

X Hao, W Zhang, B Jiao, Q Yang, X Zhang… - Frontiers in Aging …, 2023 - frontiersin.org
Background The retina imaging and brain magnetic resonance imaging (MRI) can both
reflect early changes in Alzheimer's disease (AD) and may serve as potential biomarker for …

Hemispheric patterns of recruitment of object processing regions in early Alzheimer's Disease: A study along the entire ventral stream

NS Canário, LP Jorge, IJ Santana… - Journal of …, 2023 - content.iospress.com
Background: Investigation of neural response patterns along the entire network of
functionally defined object recognition ventral stream regions in Alzheimer's disease (AD) is …

Immunotherapy with Cleavage-Specific 12A12mAb Reduces the Tau Cleavage in Visual Cortex and Improves Visuo-Spatial Recognition Memory in Tg2576 AD …

V Latina, M De Introna, C Caligiuri, A Loviglio, R Florio… - Pharmaceutics, 2023 - mdpi.com
Tau-targeted immunotherapy is a promising approach for treatment of Alzheimer's disease
(AD). Beyond cognitive decline, AD features visual deficits consistent with the manifestation …

Functional connectivity favors aberrant visual network c-Fos expression accompanied by cortical synapse loss in a mouse model of Alzheimer's disease

OJ L'Esperance, J McGhee, G Davidson, S Niraula… - Biorxiv, 2023 - biorxiv.org
While Alzheimer's disease (AD) has been extensively studied with a focus on cognitive
networks, sensory network dysfunction has received comparatively less attention despite …