Recognizing the importance of leukocyte trafficking in inflammation led to some therapeutic
breakthroughs. However, many inflammatory pathologies remain without specific therapy …

The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …

Hemocompatibility of blood-contacting biomaterials is one of the most important criteria for
their successful in vivo applicability. Thus, extensive in vitro analyses according to ISO …

When nanoparticles are intravenously injected into the body, complement proteins deposit
on the surface of nanoparticles in a process called opsonization. These proteins prime the …

Protein adsorption is considered to be the most important factor of the interaction between
polymeric biomaterials and body fluids or tissues. Water‐mediated hydrophobic and …

Deposition of complement factors (opsonization) on nanoparticles may promote clearance
from the blood by macrophages and trigger proinflammatory responses, but the mechanisms …

A key for long-term survival and function of biomaterials is that they do not elicit a detrimental
immune response. As biomaterials can have profound impacts on the host immune …

With the expansion of the nanomedicine field, the knowledge focusing on the behavior of
nanoparticles in the biological milieu has rapidly escalated. Upon introduction to a complex …

Biomaterials are regularly used in various types of artificial tissues and organs, such as
oxygenators, plasmapheresis equipment, hemodialysers, catheters, prostheses, stents …

Biological membranes often play important functional roles in biomimetic drug delivery
systems. We discover that the circulation time and targeting capability of biological …