Substrate specificity of pyrimidine nucleoside phosphorylases of NP-II family probed by X-ray...

Calculation of Free Energy of Binding for Widely Specific Pyrimidine-Nucleoside Phosphorylase and Suspected Inhibitors

PA Eistrikh-Heller, SV Rubinsky, VR Samygina… - Russian Journal of …, 2022 - Springer
Searching for a specific inhibitor of pyrimidine nucleoside phosphorylase (PyNP) was a
central objective of the work. The search was carried out by modeling protein–ligand …
被引用次数：2 相关文章

X-ray Structural Studies of Proteins at the Shubnikov Institute of Crystallography of the Russian Academy of Sciences

IP Kuranova, AA Lashkov, VR Samygina - Crystallography Reports, 2024 - Springer
The development and formation of X-ray crystallography of macromolecules, or protein
crystallography, is one of the most important achievements of science in the 20th century …
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Crystal structure of pyrimidine-nucleoside phosphorylase from Bacillus subtilis in complex with imidazole and sulfate

VV Balaev, II Prokofev, AG Gabdoulkhakov… - … Section F: Structural …, 2018 - journals.iucr.org
Pyrimidine-nucleoside phosphorylase catalyzes the phosphorolytic cleavage of thymidine
and uridine with equal activity. Investigation of this protein is essential for anticancer drug …
被引用次数：7 相关文章 所有 10 个版本

A thermostable pyrimidine nucleoside phosphorylase from Brevibacillus borstelensis LK01 for synthesizing halogenated nucleosides

K Liu, Y Zhou, J Zhang, J Chu, Y Zhang, B He - Biotechnology letters, 2017 - Springer
Objective To isolate a thermostable pyrimidine nucleoside phosphorylase (PyNP) from
mesophilic bacteria by gene mining. Results Bb PyNP from Brevibacillus borstelensis LK01 …
被引用次数：5 相关文章 所有 7 个版本

Неконкурентный ингибитор тимидинфосфорилаз

ВВ Балаев, АА Лашков, ТМ Гараев - 2019 - elibrary.ru
Изобретение относится к области биохимии. Предложен неконкурентный ингибитор
тимидинфосфорилаз пептидной природы H-Trp-Met (О 2)-Phe-NH 2. Изобретение …
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